Abstract:
Three cases of laryngeal radionecrosis are reported. In two cases partial surgery after radiotherapy probably triggered the radionecrosis. All patients were treated successfully with medical therapy. Laryngeal radionecrosis is an uncommon complication of radiotherapy for carcinoma of the head and neck. The interval between conclusion of radiation therapy and development of radionecrosis ranges from 3 to 12 months. Neither computed tomography nor magnetic resonance imaging differentiate between necrotic tissue and recurrent tumor. Humidification, broad spectrum antibiotics, steroids, and hyperbaric oxygen, with or without surgery, are successful in many cases.
Morales, del Valle, Rubio, Mazón, Rama, , , , (1997). [Diagnosis and treatment of laryngeal radionecrosis]. Acta otorrinolaringologica espanola, 1997 May;48(4):295-8. https://www.ncbi.nlm.nih.gov/pubmed/9376141