Abstract:
Establish a pattern of behavior and treatment algorithm at the onset of hematuria in patients with a previous history of pelvic radiation, checking for this different treatment options reflected in the literature. Through performing a PubMed literature review of articles related to IC lies, searching items includes the different treatment options: intravesical hyaluronic acid, conjugated estrogens, pentosan polysulfate, oral aminocaproic acid, recombinant factor VIIa, hyperbaric chamber, embolization, aluminum intravesical, Helmstein ball and formalin. Limits the search to english or spanish publications and excluding those related to animal experimentation. Every option is exposed, referring to the physiopathology, dosage regimen and administration, side effects and treatment efficacy. Once patient hemodynamic stabilization is achieved, and after rule out bladder tumors injuries and /or haemathuria originating from the upper urinary tract, treatment should start rolling. To know different treatment options and patterns of administration will allow the urologist to obtain a higher rate of success in the difficult management of this condition.
Martínez-Rodríguez, Areal Calama, Buisan Rueda, González Satue, Sanchez Macias, Arzoz Fabregas, Gago Ramos, Bayona Arenas, (2010). [Practical treatment approach of radiation induced cystitis]. Actas urologicas espanolas, 2010 Jul;34(7):603-9. https://www.ncbi.nlm.nih.gov/pubmed/20540877