Abstract:
Regression analyses compared 41 type 2 diabetes (T2D) and 131 non-T2D cognitively normal elderly males on the associations of arterial wall function measures [large artery elasticity index (LAEI), small artery elasticity index (SAEI), systemic vascular resistance (SVR), and total vascular impedance (TVI)] with cognitive performance (memory, language, and executive functions), controlling for socio-demographic and cardiovascular factors. Higher LAEI and lower TVI were significantly associated with better executive functions performance in T2D but not in non-T2D subjects. Lower TVI was more associated with better language performance in T2D. Results suggest that arterial wall function is associated with cognition in T2D.
Ravona-Springer, Haratz, Tanne, Schmeidler, Efrati, Rosendorff, Beeri, Silverman, (2015). Arterial wall function is associated with cognitive performance primarily in elderly with type 2 diabetes. Journal of Alzheimer’s disease : JAD, 2015 ;44(2):687-93. https://www.ncbi.nlm.nih.gov/pubmed/25352451