Abstract: The aim of this study was to review the available literature and define clinical practice guidelines for the use of agents for the prevention and treatment of gastrointestinal mucositis. A systematic review was conducted by the Mucositis Study Group of the...
Cancer
Successful resuscitation after carbon dioxide embolism during laparoscopy.
Abstract: Venous air embolism (VAE) is a rare life-threatening complication that can occur during laparoscopy. A 50-year-old previously healthy woman underwent laparoscopic cholecystectomy and liver cyst fenestration. Immediately after the surgeon had left the...
Hyperbaric oxygen therapy reduces COX-2 expression in a dimethylhydrazine-induced rat model of colorectal carcinogenesis.
Abstract: A better understanding of oncogenesis mechanisms should result in more effective approaches to colorectal cancer (CRC) treatment and prevention. Hyperbaric oxygen (HBO2) therapy is indicated as adjuvant treatment for infectious diseases as well as hypoxic...
Management of Bartholin’s gland carcinoma using high-dose-rate interstitial brachytherapy boost.
Abstract: To describe the patterns of use, clinical outcomes, and dose-volume histogram parameters of high-dose-rate interstitial brachytherapy (HDR-ISBT) in the management of Bartholin's gland cancer. Five patients with Stage II-III Bartholin's gland carcinoma...
Incidence and clinical course of radionecrosis in children with brain tumors. A 20-year longitudinal observational study.
Abstract: Radionecrosis (RN) in children treated for brain tumors represents a potentially severe long-term complication. Its diagnosis is challenging, since magnetic resonance imaging (MRI) cannot clearly discriminate between RN and tumor recurrence. A retrospective...
Hyperbaric oxygen therapy (HBOT) in case of hemorrhagic cystitis after radiotherapy.
Abstract: We present the effect of hyperbaric oxygen therapy (HBOT) after radiotherapy for cancer in the pelvic cavity resulting in hematuria. Increasing the pressure of oxygen (PO2) in ischemic tissues favors the formation of new blood vessels and increases the...
Hyperbaric oxygen therapy and cancer–a review.
Hypoxia is a critical hallmark of solid tumors and involves enhanced cell survival, angiogenesis, glycolytic metabolism, and metastasis. Hyperbaric oxygen (HBO) treatment has for centuries been used to improve or cure disorders involving hypoxia and ischemia, by enhancing the amount of dissolved oxygen in the plasma and thereby increasing O(2) delivery to the tissue. Studies on HBO and cancer have up to recently focused on whether enhanced oxygen acts as a cancer promoter or not. As oxygen is believed to be required for all the major processes of wound healing, one feared that the effects of HBO would be applicable to cancer tissue as well and promote cancer growth. Furthermore, one also feared that exposing patients who had been treated for cancer, to HBO, would lead to recurrence.
Gracilis muscle interposition with primary rectal without urethral repair for moderate sized rectourethral fistula caused by brachytherapy for prostate cancer: a case report.
Abstract: There is a 0.16% chance of a rectourethral fistula after prostate brachytherapy monotherapy using Palladium-103 or Iodine-125 implants. We present an unusual case report of a rectourethral fistula following brachyradiotherapy monotherapy for prostate...
Hyperbaric oxygen therapy for late rectal and bladder toxicity after radiation in prostate cancer patients. A symptom control and quality-of-life study.
Abstract: Fuentes-Raspall, Inoriza, Martí-Utzet, Auñón-Sanz, Garcia-Martin, Oliu-Isern, , , (2012). Hyperbaric oxygen therapy for late rectal and bladder toxicity after radiation in prostate cancer patients. A symptom control and quality-of-life study. Clinical...
Re-oxygenation causes hypoxic tumor regression through restoration of p53 wild-type conformation and post-translational modifications.
Abstract: Hypoxic tumors are resistant to conventional therapies through indirect mechanisms such as the selection of resistant phenotype under chronic hypoxia. Hyperbaric oxygen (HBO) therapy has been shown to increase oxygen level and induce apoptosis in hypoxic...