This study was designed to investigate therapeutic effects of hyperbaric oxygen on experimentally induced colitis in rats by assessing oxidative tissue damage, neutrophil accumulation and histological changes.
Six groups of animals were used. No procedures were done in the sham group. In the vehicle group, 50% ethanol-induced colitis, and in four other groups, 2,4,6-trinitrobenzene sulphonic acid-induced colonic inflammation was achieved. In acute and chronic colitis non-treatment groups, no other procedure was done. In acute and chronic colitis hyperbaric oxygen treatment groups, rats underwent hyperbaric oxygen treatment for two or fourteen days.
Abstract: Hyperbaric oxygen therapy has been used to successfully treat perineal Crohn's disease. We describe the first successful use of hyperbaric oxygen therapy in the treatment of ulcerative colitis, refractory to conventional therapies. Therapy consisted of 30...
Abstract: Hyperbaric oxygen therapy has been used to successfully treat perineal Crohn's disease. We describe the first successful use of hyperbaric oxygen therapy in the treatment of ulcerative colitis, refractory to conventional therapies. Therapy consisted of 30...
Abstract: A 17-year-old boy presented with Fournier gangrene associated with previously undiagnosed Crohn ileocolitis. Fournier gangrene was managed by débridement, broad-spectrum antibiotics, and hyperbaric oxygen. A diverting ileostomy was performed before skin...
Abstract: Takeshima, Makiyama, Doi (1999). Hyperbaric oxygen as adjunct therapy for Crohn's intractable enteric ulcer. The American journal of gastroenterology, 1999 Nov;94(11):3374-5. https://www.ncbi.nlm.nih.gov/pubmed/10566754
Abstract: [No Authors Listed] (1999). Hyperbaric oxygen therapy for wound healing--part III. Tecnologica. MAP supplement. Blue Cross and Blue Shield Association. Medical Advisory Panel, 1999 Oct;():11-4. https://www.ncbi.nlm.nih.gov/pubmed/10848084
Abstract: Perineal lesions are a frequent and troublesome complication of Crohn's disease. Although there are various surgical and medical therapeutic regimens available to treat these lesions, all have significant associated morbidity, mortality, and toxicity....
Abstract: Treatment of perianal inflammatory lesions in Crohn's disease (CD) is unsatisfactory and novel treatment modalities are pursued. We have recently reported a good clinical effect of hyperbaric oxygen (HBO) treatment in perianal CD. In the present study, seven...
Abstract: Sipahi, Damião, de Sousa, Barbutti, Trivellato, Esteves, D'Agostino, Laudanna (1996). Hyperbaric oxygen: a new alternative in the treatment of perianal Crohn's disease. Revista do Hospital das Clinicas,...
Abstract: A total of 114 of 195 patients with Crohn's disease had perianal involvement. The average age at the beginning of symptomatology was 30.3 years. The interval between symptoms and diagnosis was 3.1 years. PAC was associated with colonic disease and in these...
