HBOT Conversations:
Laurie Anderson (Part 3)
Healing COVID with HBOT
Dr. Laurie is a Doctor of Pharmacy, and a graduate of the University of North Carolina – Chapel Hill (UNC-CH) School of Pharmacy and the Pharmacy Practice Residency Program at the University of California – San Francisco (UCSF). Dr. Laurie spent many years in clinical practice, first as a neurosurgery clinical pharmacist at UCSF Medical Center and then as a general medicine and critical care clinical pharmacist at Duke Medical Center. For the past 14 years Dr. Laurie has been working in industry, and is currently a safety scientist in early phase drug development, designing safety strategies for First Time in Human clinical trials.
Through her own journey navigating chronic illness, Dr. Laurie has explored and embraced many forms of alternative and non-traditional medicine to support her body for healing. She has gravitated towards practitioners and modalities that treat the whole patient, with the mantra that tending to mind, body and spirit is the true key to lasting health. Over the years, Dr. Laurie has discovered that this often leads to a ‘less is more’ approach. She discovered HBOT when she was struggling to heal from COVID, and now tells anyone who will listen about the power of oxygen and pressure.
Watch the Podcast
We continue Dr. Laurie Anderson’s HBOT News Network interview, diving in deeper to discuss our veteran population, does HBOT have a therapeutic index, and what is the research telling us about the HBOT industry.
Her interview has been released as a three part series. Part 1 and Part 2 has already been released with both focusing on her HBOT journey with COVID & Lyme Disease.
In Part 3 of Laurie’s podcast the conversation shifts. It starts with the medical industry and the unfortunate “bad rap” that Hyperbaric Oxygen sometimes receives. Dr, Laurie refers to HBOT as a gift, so it’s truly unfortunate when the media focuses on the negative instead of the positive, influencing the public to not even try this life saving therapy. Research trials are discussed, including the problems that the hyperbaric industry has identified in the sham, placebo and/or control group when researchers try to mimic HBOT with little pressure and they discover that everyone starts to improve. Those of us in this industry understand and effortlessly work to enlighten others that any amount of pressure is good and therapeutic.
The topic of our US military and the high rate of suicide among our service man and women arises. Is there a solution to the veteran suicide epidemic our country is facing? It appears there is. di Girolamo speaks of Patriot Hyperbarics in Tulsa, and the success they have had treating veterans with Hyperbaric Oxygen Therapy.
“The Patriot Clinics in Tulsa treated some 500 veterans with PTSD, with donated money, donated chambers, and healed them. Most of them war-fighters, were in a bedroom, locked in the dark for years and years, like seven, ten years. And then they found Patriot Clinics and they got 40 treatments and then they got their executive function back. Some of them starting businesses. I saw videos of guys, you know, in the car on their way to the clinic on the first day and then on the 40th day, talking about their experience, it was just amazing.
There wasn’t some combined study about that. 500 souls were saved that didn’t commit suicide, they worked their way out of it.”
Dr. Laurie, who is a Doctor of Pharmacy, brings up an excellent point, and one that we’ve never discussed before on HBOT News. We know that the FDA ultimately states that oxygen is a drug, and you are required to have a prescription for it. But does Hyperbaric Oxygen have a therapeutic index like other drugs? And if so… how would a patient know they have reached the therapeutic index and how long is a patient at the therapeutic index? She explains it like this…
“If I apply this to drugs, like with a drug we would want to keep the level, generally, we try to keep the level of a drug in the blood inside the therapeutic index, right? So sometimes, depending on the half life of the drug, you can be in your therapeutic index by taking it once a day so you trickle up and down in between that therapeutic index. Some drugs have a shorter half life and you have to take it twice a day to stay in that therapeutic index.
So what keeps you in whatever is the defined therapeutic index, if that can be translated to oxygen therapy, you know, is it daily? Is it twice a day?”
di Girolamo wonders if in 20 years from now the industry will look back on this conversation and be shocked that we weren’t more focused on the therapeutic index. He stresses that the hyperbaric industry can’t even come together and decide the specific definition of hyperbaric oxygen, much less all these variables that Dr. Laurie has opened our eyes to.
Dr. Laurie ends her time here with HBOT News stressing that for her HBOT healed her during a very sick time with COVID, and it helped her with many of the Lyme Disease symptoms she struggled with for years. It worked for her, and she said it’s definitely worth a try to see if it can work for you.
Guests

Dr. Laurie Anderson, Pharm.D.
Through her own journey navigating chronic illness, Dr. Laurie has explored and embraced many forms of alternative and non-traditional medicine to support her body for healing. She has gravitated towards practitioners and modalities that treat the whole patient, with the mantra that tending to mind, body and spirit is the true key to lasting health. Over the years, Dr. Laurie has discovered that this often leads to a ‘less is more’ approach.
When not working, Dr. Laurie is an avid gardener, ballroom dancer and traveler with her husband. Remaining curious and finding joy in every day are her super powers.
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Brain perfusion imaging with voxel-based analysis in secondary progressive multiple sclerosis patients with a moderate to severe stage of disease: a boon for the workforce.
The present study was carried out to evaluate cerebral perfusion in multiple sclerosis (MS) patients with a moderate to severe stage of disease. Some patients underwent hyperbaric oxygen therapy (HBOT) and brain perfusion between before and after that was compared. We retrospectively reviewed 25 secondary progressive (SP)-MS patients from the hospital database. Neurological disability evaluated by Expanded Disability Status Scale Score (EDSS). Brain perfusion was performed by (99 m) Tc-labeled bicisate (ECD) brain SPECT and the data were compared using statistical parametric mapping (SPM). In total, 16 patients underwent HBOT. Before HBOT and at the end of 20 sessions of oxygen treatment, 99mTc-ECD brain perfusion single photon emission computed tomography (SPECT) was performed again then the results were evaluated and compared. Brain perfusion was performed by (99 m) Tc-labeled bicisate (ECD) brain SPECT and the data were compared using statistical parametric mapping (SPM). A total of 25 SP-MS patients, 14 females (56 %) and 11 males (44 %) with a mean age of 38.92 ± 11.28 years included in the study. The mean disease duration was 8.70 ± 5.30 years. Of the 25 patients, 2 (8 %) had a normal SPECT and 23 (92 %) had abnormal brain perfusion SPECT studies. The study showed a significant association between severity of perfusion impairment with disease duration and also with EDSS (P <0.05). There was a significant improvement in pre- and post-treatment perfusion scans (P <0.05)
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The medical treatment of ischemic ulcers in patients with systemic sclerosis remains difficult. Despite the major help provided by vasodilator treatments, the risk of spontaneous or surgical amputation remains high. A 48-year-old female patient from Guadeloupe was treated in our department for diffuse systemic sclerosis present for 15 years complicated by lung, joint and digestive involvement, and associated with severe Raynaud’s phenomenon. The clinical course was marked by the occurrence of multiple ischemic ulcers, which were resistant to conventional medical treatment and resulted in two surgical amputations (to the 2nd and 3rd interphalangeal joints of the toes of the left foot). Treatment with an endothelin-receptor antagonist and a calcium inhibitor was then introduced for secondary prevention. Two years later, the patient consulted for a further ischemic ulcer of the left 4th toe. She refused the proposed treatment with iloprost. Because of the unfavorable outcome and the absence of therapeutic alternative to amputation, hyperbaric oxygen therapy was initiated. Thirty 90-minutes sessions of pure oxygen at 2.5 ATA were conducted over a 10-week period. Complete healing was obtained after 8 months. We report herein a clinical case illustrating the efficacy of hyperbaric oxygen therapy for the treatment of ischemic ulcers of the toes in systemic sclerosis.
