Pilot Study Exploring the Use of Hyperbaric Oxygen in Autologous Peripheral Blood Stem Cell Transplant

Description:

The post stem cell transplant complications of neutropenic fever and mucositis, related to
the chemotherapy and/or radiation on hematopoietic tissue administered prior to peripheral
blood stem cell transplant, are reversible upon neutrophil count recovery. The investigators
will investigate the use of hyperbaric oxygen as an intervention to shorten neutropenia
post-high-dose chemotherapy and autologous peripheral blood stem cell transplant. The idea of
using hyperbaric oxygen therapy in autologous stem cell transplantation is based on the
investigators pre-clinical work that supported the use of hyperbaric oxygen to improve
umbilical cord blood (cluster of differentiation 34) CD34+ stem cell transplantation.

Condition:

Multiple Myeloma

Treatment:

Administration of hyperbaric oxygen

Start Date:

March 2014

Sponsor:

University of Kansas Medical Center

For More Information:

https://clinicaltrials.gov/show/NCT02087657