The Effect of Unilateral Spinal Anaesthesia and Psoas Compartment With Sciatic Block on the Postoperative Pain Management in Total Knee Artroplastic Surgery
Description:
In this prospective, randomised, multicentric and single-blind study, 60 patients who were
diagnosed with gonarthrosis in the outpatient clinic of Ordu University Training Hospital and
Ordu State Hospital between January 1, 2015 and June 30, 2015, and planned for total knee
arthroplasty, were included. Patients who were allergic to local anaesthetics, had
neurological disease, had infections in the intervention area, did not cooperate, or did not
agree to the intervention were excluded from the study. After receiving informed consent from
the patients, they were divided into two groups using the closed envelope method: the USA
Group was the spinal anaesthesia (SA) group (n = 30), and the PCS group was the PCB and
sciatic nerve block group (n = 30). All of the patients planned for surgery were monitored in
terms of non-invasive arterial blood pressure, heart rate (HR) and peripheral haemoglobin
oxygen saturation (SpO2). Peripheral vascular access was established using an 18-G cannula
before the block operation, and 500 ml of 0.9% NaCl solution was infused for 20 minutes
followed by the intravenous administration of 0.07 mg/kg midazolam (Dormicum®; Roche, Basel,
Switzerland). The haemodynamic parameters were recorded every 5 minutes until the end of the
preoperative and perioperative operation period. Next, 2 ml of hyperbaric bupivacaine
hydrochloride (Marcain Heavy 0.5%; AstraZeneca®, London, UK) was administered to patients in
the USA group in the lateral decubitus position, after regional sterilisation, through the
selected intervertebral space (L4-L5 or L3-L4) using a 25-G Quincke spinal injector (B.
Braun®, Melsungen, Germany). After remaining in this position for 15 minutes after the
procedure, the patients were changed to the supine position. Patients in the PCS group were
changed to the lateral decubitus (Simms) position. Following the sterilisation and covering
procedures required for blockade of the lumbar plexus somatic nerves, the abdominal settings
were selected on the ultrasound device (Mindray DC-T6 VET®, Shenzhen, China). The depth was
set at 11-12 cm, and the frequency was set at 4-8 MHz. A convex ultrasonography (USG) probe
was placed 4 cm laterally on the middle line at the L3-L5 level. The transverse process was
longitudinally identified using an USG probe. The ‘trident sign’ (three-pronged spear
appearance) acoustic shadow of the transverse process is characteristic. After viewing the
psoas muscle at the depth of the transverse process, the needle was inserted using an
out-plane approach. While using a nerve stimulator simultaneously (Stimupleks A; B. Braun®,
Melsungen AG, Germany), the stimulation current was reduced to the 0.5-1.0 mA level when
contraction of the quadriceps muscle was observed, and 20 ml of local anaesthetic (5 ml of 2%
lidocaine + 15 ml of 0.5% bupivacaine) was injected. The local anaesthetic was observed to
disperse around the lumbar plexus with USG. Sciatic nerve block was applied as follows: the
patients’ positions were not changed, and the skin was disinfected in the same position
(lateral decubitus position). Following the required covering process, the USG settings were
applied for optimum visualisation. The depth was set as 3-6 cm, and frequency as 2-8 MHz. The
convex USG probe was placed in the subgluteal area in the transverse position. After
determining the sciatic nerve, the injector was inserted into the lateral edge of the probe
as in-plane and proceeded towards the nerve. When using the nerve stimulator simultaneously
(Stimupleks A; B. Braun®), the stimulation current was reduced to 0.2-0.5 mA until
contractions became visible. The local anaesthetic was observed to disperse around the
sciatic nerve with USG by administering 20 ml of local anaesthetic (5 ml of 2% lidocaine + 15
ml of 0.5% bupivacaine) following negative aspiration with the injector. The patients were
changed to the supine position. Surgery was allowed when effective sensory block reached with
at least a T10 dermatome.
After the procedure, the patients were changed to the supine position. The application times
of both techniques were recorded as the technique application times. While the analgesia
level was evaluated using the pinprick test, the degree of motor block was assessed using the
modified Bromage scale (0: no block, 1: hip flexion is blocked when the knee is extended, 2:
knee flexion is blocked, 3: full motor block). Additionally, the sensory and motor blocks
were evaluated at 5-minute intervals using the measurements of the haemodynamic parameters
after the administration of medications. No case was excluded from the study because of block
failure; thus, the data of all the cases in both groups were analysed.
Surgical intervention was initiated after the development of a full motor block. The time
from the beginning of surgical incision until the completion of the procedure was recorded as
the operation period. A decrease in the mean basal arterial pressure of 25% or more was
considered as hypotension; in this case, ephedrine was administered as 5 mg intravenously
(i.v.), and 5 ml/kg additional crystalloid fluid was given. Heart rates less than 50
beats/minute were considered as bradycardia, and atropine was administered as 0.5 mg i.v. All
of the patients were administered 3 l/minute O2 through the mask and 5 ml/kg/hour maintenance
crystalloid i.v. fluid during the surgery. The motor block return time and first analgesic
requirement time were recorded.
Condition:
Postoperative Analgesia
Treatment:
intratechal (subarachnoidal )injection
Start Date:
January 2015
Sponsor:
T.C. ORDU ÜNİVERSİTESİ
For More Information:
https://clinicaltrials.gov/show/NCT03021421