Suppress Entropy

In the realm of hyperbaric medicine, the conventional wisdom holds that increased pressure and oxygen concentration work together to improve tissue oxygenation, fight off infection, and promote healing. But what if the effectiveness of hyperbaric oxygen therapy (HBOT) goes beyond these well-understood mechanisms?  Dr. Edward Fogarty recently shed light on an intriguing concept: the idea that pressure suppresses entropy and is thus a fundamental benefit of hyperbaric medicine. This blog post aims to explore this theory and consider its implications for understanding disease and improving medical therapies.

The Entropy Connection

Entropy is a measure of disorder or randomness in a system. In biological systems, the concept of entropy extends to the chaotic environment at the cellular level, characterized by fluctuating concentrations of ions, proteins, and other biomolecules. This chaos can be both a symptom and a driver of disease, perpetuating a cycle of inflammation, hypoxia, and other harmful mechanisms.

Fogarty suggests that pressure, as applied in hyperbaric medicine, serves as an entropy suppressor, imposing a kind of “order” on the disorderly molecular environment within cells. The idea echoes the physics principle that increased pressure can drive molecules into a more ordered state, reducing entropy.

Brownian Motion and Active Transport

Fogarty points out the role of Brownian Motion, the random movement of particles suspended in a fluid, as a part of gases dissolved in the cellular landscape. The Brownian Motion does play a role in the active transport of proteins and other molecules across cell membranes. By applying pressure, the theory posits that we could make this transport more efficient, thereby assisting cellular function and reducing entropy.

The Cascade Effect and Disease

Most diseases are not the result of a single malfunctioning mechanism but a cascade of them, exacerbating each other in a vicious cycle. This cascade can include inflammation, hypoxia, and many other harmful processes, creating a disordered, high-entropy environment at the cellular and systemic levels. If pressure does indeed suppress entropy, it stands to reason that HBOT could be beneficial in breaking this cascade, addressing the root cause of various diseases rather than merely alleviating symptoms.

Implications for Medical Therapies

The entropy-suppressing effect of pressure could offer insights into enhancing the efficacy of other treatments as well. If we view medications, supplements, and functional therapies through the lens of entropy suppression, it opens the door for more synergistic approaches to treatment. By combining these therapies with hyperbaric medicine, we may find that their effectiveness is significantly magnified.


Fogarty’s concept of pressure as an entropy suppressor offers an intriguing new angle on the benefits of hyperbaric medicine. By viewing disease as a high-entropy state and applying pressure to restore order, we may be uncovering a fundamental principle that could revolutionize our approach to treating a wide range of conditions. While more research is needed to substantiate these claims, the theory presents a compelling avenue for future medical exploration.

So, the next time you think about hyperbaric medicine, consider not just the increased oxygen levels but also the fascinating potential of pressure to suppress entropy, impose molecular order, and possibly change our understanding of disease management.

Disclaimer: This blog post aims to explore a theory and should not replace professional hyperbaric medical advice. Always consult with hyperbaric healthcare providers for hyperbaric treatment and protocols.