Abstract: Huang, , , , , , , , (). Adjunctive hyperbaric oxygen therapy for diabetic foot ulcers: An editorial perspective. Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc,...
Diabetes
Impact of hyperbaric oxygen on diabetic ulcers is unaffected by glycemic control.
Abstract: Hyperbaric oxygen (HBO2) therapy is an established intervention for treating chronic diabetic lower extremity ulcers, but the impact of glycemic control on its efficacy has not been determined. The purpose of this study was to evaluate the impact of blood...
Glycosylated hemoglobin and hyperbaric oxygen coverage denials.
Abstract: Some Medicaid and Medicare fiscal intermediaries are denying hyperbaric oxygen (HBO2) therapy for diabetic foot ulcer (DFU) patients if the glycosylated hemoglobin (HbA1c) > 7.0%. We performed multiple PubMed searches for any diabetic wound healing clinical...
A clinical practice guideline for the use of hyperbaric oxygen therapy in the treatment of diabetic foot ulcers.
Abstract: The role of hyperbaric oxygen (HBO2) for the treatment of diabetic foot ulcers (DFUs) has been examined in the medical literature for decades. There are more systematic reviews of the HBO2/DFU literature than there have been randomized controlled trials...
Hyperbaric oxygen therapy reduces the risk of QTc interval prolongation in patients with diabetes and hard-to-heal foot ulcers.
Abstract: Heart rate corrected QT (QTc) interval prolongation is a risk factor associated with increased mortality. Hyperbaric oxygen therapy (HBO) has previously been shown to have acute beneficial effects on QTc dispersion. The aim of this study was to evaluate...
Hyperbaric oxygen therapy as an adjunctive treatment for diabetic foot wounds: a comprehensive review with case studies.
Abstract: Complications associated with diabetes are often expensive to treat, and commonly include foot ulceration. While most diabetic foot ulcers heal with standard treatment, when standard treatment measures fail, adjunctive therapies must be considered. We...
Clinical Trial – Efficacy of the Combination of Isosorbide Dinitrate Spray and Chitosan in Diabetic Foot Ulcers
The prevalence of diabetic foot ulceration in the diabetic population is 4-10%; the condition
is more frequent in elder patients. It is estimated that about 5% of all patients with
diabetes present a history of foot ulceration, while the lifetime risk of diabetic patients
developing this complication is 15%. The majority (60-80%) of foot ulcers will heal, while
10-15% of them will remain active, and 5-24% of them will finally lead to limb amputation
within a period of 6-18 months after the first evaluation , 2 out of 3 patients with a limb
amputation could also be involved in a new amputation in the next year; higher or in the
other leg , Eighty-five percent of lower-limb amputations in patients with diabetes are
preceded by foot ulceration. The management of chronic diabetic foot ulcers (DFU) suggests
multi-disciplinary approaches including control of diabetes, orthotic shoe wear, off-loading
device, wound care and surgery in selected cases. However, treatment of DFU remains
challenging because of unsatisfactory results from surgical and non-surgical treatments. Many
adjunctive therapies are designed to improve the care of DFU including negative pressure
wound therapy , ultrasound, recombinant human platelet-derived growth factor-BB (rPDGF-BB)
Hyperbaric oxygen and acellular matrix product among others.
Chronic wound repair and healing in older adults: current status and future research.
Abstract: Older adults are more likely to have chronic wounds than younger people, and the effect of chronic wounds on quality of life is particularly profound in this population. Wound healing slows with age, but the basic biology underlying chronic wounds and the...
Clinical Trial – Effectiveness of Aurix Therapy in Diabetic Foot Ulcers
The aim of this trial is to demonstrate the effectiveness of complete wound healing in a
prospective, open-label, randomized trial in which diabetic food ulcers (DFU) will be treated
using Aurix plus Usual and Customary Care (UCC) and compared to a group receiving just UCC as
provided in up to 100 U.S. wound centers
Therapeutic approach to "diabetic foot" complications.
Abstract: The series of ulcers of the lower extremities known as "diabetic foot" is a common complication of diabetes and the chief cause of admission to hospital. The causes may be numerous but the main ones are distal symmetric neuropathy and peripheral...