The investigators have previously studied the efficacy of hyperbaric oxygen therapy (HBOT) as
a treatment for Fibromyalgia syndrome (FMS) in a prospective, active control, crossover
clinical trial. The results demonstrated significant amelioration of all FMS symptoms, with
significant improvement in life quality; furthermore, the investigators were able to
demonstrate significant neuroplasticity on SPECT imaging, with a decrease of the
hyperactivity in posterior regions and elevation of the reduced activity in frontal areas.
In this study, the investigators intend to both repeat and expand the investigator’s previous
findings, treating FMS patients with history of emotional trauma with HBOT, while performing
an extensive of evaluation both before and after treatment.
In the current study, the investigators plan to compare HBOT to current standard of care of
FMS (pharmacological and non – pharmacological).
Regional anesthesia is a popular anesthetic method in patients who will undergo an inguinal
hernia operation. Researchers known that pain in the operating area is a complaint that
impairs the quality of life for patients in the long term after the operation. In addition to
regional anesthesia, has planned to investigate the effects of applying another drug near the
surgery area on pain that may develop in the long term.
Abstract: BackgroundPrevious studies have shown that hyperbaric oxygen therapy (HBOT) can improve the motor functions and memory of post-stroke patients in the chronic stage. ObjectiveThe aim of this study is to evaluate the effects of HBOT on overall cognitive...
In the investigator’s institute there is ongoing treatment of different patients with
cognitive deficits using Hyperbaric oxygen therapy (HBOT). These patients undergo
neuro-cognitive function computerized tests before and after treatment.
The aim of this study was to retrospectively evaluate the cognitive changes before and after
HBOT in different patients populations.
Abstract: Hyperbaric oxygen (HBO) treatment promotes early recovery from muscle injury. Reactive oxygen species (ROS) upregulation is a key mechanism of HBO, which produces high O2 content in tissues through increased dissolution of oxygen at high pressure. Nitric...
The objective of this study is to compare the incidence of postoperative urinary retention
related to spinal anesthesia with morphine and spinal anesthesia associated with peripheral
blockade in orthopedic procedures of lower limbs. Secondary objectives are assessing the
incidence of nausea and vomiting; postoperative pain and opioid consumption at 24 hours after
surgery with each of the techniques. A total of 52 patients submitted to a lower limb
orthopedic procedure were randomized to the intervention groups: spinal anesthesia with
morphine versus spinal anesthesia without opioid associated with peripheral nerve block.
After surgery, bladder ultrasound will be performed in post-anesthesia care unit to identify
urinary retention and patients will be followed for 24 hours to assess outcomes.
Spinal anaesthesia has the advantage that produced nerve block by the injection of local
anaesthetic into cerebrospinal fluid (CSF). However, the greatest challenge in spinal
anaesthesia is to control the spread of local anaesthetic through the CSF to provide a block
which is adequate for the proposed surgery without unnecessary extensive spread, and
increased risk of complications.
The aim of the current study was to examine the effect of short-term HBOT (hyperbaric oxygen
treatments) on a range of cognitive abilities. The current study examined whether there is a
HBOT-related short-term cognitive improvement and, if so, what specific cognitive abilities
are improved by the intervention.
Participants were randomized to perform cognitive tasks in one of two chambers with two
different clinical environments: (a) HBOT condition: (2 ATA (atmosphere absolute) 100% oxygen
for 90 minutes). (b) Control condition: in which the chamber was not pressurized (Normobaric
condition- 1 ATA for 90 minutes).
1. To determine the reliability and performance of the Dexcom G6® continuous glucose
monitoring (CGM) system in patients with diabetes undergoing hyperbaric oxygen (HBO2)
exposure. The study-specific blood glucose meter and CGM system are approved by the FDA
(U.S. Food and Drug Administration).
2. To determine whether HBO2 exposure causes blood glucose to drop as a result of the
treatment.
3. To determine whether HBO2 causes a change in blood glucagon (a hormone that raises blood
glucose).
Investigators will be comparing changes in blood glucose and glucagon in volunteers with
diabetes who will be exposed to a single hyperbaric oxygen treatment (pressurization to 2.4
atmospheres absolute for 90 minutes) to a control period of 2 hours where volunteers will
simulate a hyperbaric treatment while sitting in an examination room breathing room air at
sea level pressure. Investigators will be measuring blood glucose with a variety of devices
including a continuous glucose monitor, two point-of-care glucometers, and the hospital
inpatient laboratory measurement of venous blood.
