Abstract: Calcific uremic arteriopathy (CUA), termed calciphylaxis, is a rare but highly fatal clinical syndrome. There is no clearly laboratory diagnostic criteria for CUA. The medium and small arterial calcification and microthrombosis discovered by skin biopsy,...
HBOT Research
Rehabilitation for people with multiple sclerosis: an overview of Cochrane Reviews.
Multiple sclerosis (MS) is a major cause of chronic, neurological disability, with a significant long-term disability burden, often requiring comprehensive rehabilitation. To systematically evaluate evidence from published Cochrane Reviews of clinical trials to summarise the evidence regarding the effectiveness and safety of rehabilitation interventions for people with MS (pwMS), to improve patient outcomes, and to highlight current gaps in knowledge. We searched the Cochrane Database of Systematic Reviews up to December 2017, to identify Cochrane Reviews that assessed the effectiveness of organised rehabilitation interventions for pwMS. Two reviewers independently assessed the quality of included reviews, using the Revised Assessment of Multiple Systematic Reviews (R-AMSTAR) tool, and the quality of the evidence for reported outcomes, using the GRADE framework. Overall, we included 15 reviews published in the Cochrane Library, comprising 164 randomised controlled trials (RCTs) and four controlled clinical trials, with a total of 10,396 participants. The included reviews evaluated a wide range of rehabilitation interventions, including: physical activity and exercise therapy, hyperbaric oxygen therapy (HBOT), whole-body vibration, occupational therapy, cognitive and psychological interventions, nutritional and dietary supplements, vocational rehabilitation, information provision, telerehabilitation, and interventions for the management of spasticity.
Hyperbaric oxygen therapy for postoperative ischemic bronchitis after resection of lung cancer.
Hyperbaric oxygen therapy (HBOT) has been used successfully in the treatment of specific ischemic injuries, but has been a little evaluated specifically in postoperative ischemic bronchitis (POIB). The purpose of this study was to evaluate the effect of HBOT when used for POIB after resection of lung cancer. From January 1999 to December 2016, 1,100 patients underwent lymph node dissection (LND) and either anatomic pulmonary resection or lung resection with bronchoplasty for lung cancer. POIB was diagnosed by bronchoscopy. HBOT was administered after POIB was diagnosed. HBOT comprised one 60-minute session daily in the hyperbaric chamber at 2.0 absolute atmospheres with 100% oxygen.
The Effect of a 300 mBar Increase in Barometric Pressure on Digital Microcirculation in Healthy Subjects Exposed to High Altitude: Is the Use of a Portable Hyperbaric Chamber to Treat Frostbite and/or Hypothermia in the Field Indicated? (Flow_Pulse Study).
Abstract: Savina, Yann, Sandra Leal, Pascal Zellner, François Becker, Monica Piris, and Emmanuel Cauchy. The effect of a 300 mbar increase in barometric pressure on digital microcirculation in healthy subjects exposed to high altitude: Is the use of a portable...
Radiation-induced skin reactions: mechanism and treatment.
Radiotherapy (RT) is a major treatment for malignant tumors. The latest data show that >70% of patients with malignant tumors need RT at different periods. Skin changes can be experienced by up to 95% of patients who underwent RT. Inflammation and oxidative stress (OS) have been shown to be generally associated with radiation-induced skin reactions (RISRs). Inflammatory response and OS interact and promote each other during RISRs. Severe skin reactions often have a great impact on the progress of RT. The treatment of RISRs is particularly critical because advanced RT technology can also lead to skin reactions. RISRs are classified into acute and chronic reactions.
Clinical Trial – Fascia Iliaca Block for Anesthesia in Lower Limb Thromboembolectomy
The fascia iliaca block (FIB) is an anterior approach to block the lumbar plexus. It
disturbed mainly to the anterior region of the thigh by blocking the femoral nerve (LFC) and
the lateral femoral cutaneous nerve. Moreover, FIB may possibly be extended to the obturator,
ilioinguinal, genitofemoral, lateral cutaneous nerve of the thigh and over the psoas muscle
but, rarely reaches the lumbar plexus.
The fascia iliaca compartment could be detected by bony landmarks palpation and the loss of
resistance technique. Feeling two tactile ”pops” due to loss of resistance occurred during
the needle passage through the fascia lata and the fascia iliaca. Ultrasound (US) guidance of
FIB will increase the success rate and the efficacy of sensory blockade by decreasing the
needed local anesthetic amount.
Repeated exposure to hyperbaric hyperoxia affects mitochondrial functions of the lung fibroblasts.
Abstract: Hyperbaric oxygen (HBO) therapy, i.e. breathing pure oxygen under increased environmental pressures serves as a treatment for diverse medical conditions. However, elevated oxygen concentration can be detrimental to central nervous system or lungs. Our study...
Preconditioning and postoperative hyperbaric oxygen therapy to reduce skin flap erosion after osmidrosis surgery.
Abstract: Osmidrosis surgery is still recognized as one of the best ways to treat body odor, especially the liposuction assisted curettage due to the relatively small incision that does not leave any scars, which, nevertheless, may still cause many complications. One...
Cerebral air embolism during percutaneous computed tomography scan-guided liver biopsy.
Abstract: The objective of the study is to explore the etiology, clinical manifestations, imaging features, diagnosis, treatment, and prognosis of cerebral air embolism complicated computed tomography (CT) scan-guided percutaneous liver biopsy. A case of air embolism...
Hyperbaric oxygen combined with 5-aminolevulinic acid photodynamic therapy inhibited human squamous cell proliferation.
he photodynamic therapy (PDT) depends on the presence of molecular oxygen. Thus, the efficiency of PDT is limited in anoxic regions of tumor tissue and vascular shutdown. It is reported the use of hyperbaric oxygen (HBO) may enhance the efficiency of PDT. However, there are rarely studies about utilizing HBO plus PDT for treatment with human squamous cell carcinoma (SCC). Therefore, this study aimed to investigate and compare the therapeutic effect of combined therapy and PDT alone treatment. Multiple cellular and molecular biology techniques were used in the current study such as CCK-8, western blotting, flow cytometry, MDC staining and immunofluorescence assay.