Abstract: Hyperbaric oxygen therapy (HBOT) has been used as treatment for different clinical conditions, including fibromyalgia (FM). HBOT modulates brain activity, ameliorates chronic pain and modifies the ratio of immune cells. Clinical studies have provided...
HBOT Research
Vaginal natural oxygenation device (VNOD) for concomitant administration of hyaluronic acid and topical hyperbaric oxygen to treat vulvo-vaginal atrophy: a pilot study.
Abstract: This is a pilot study to evaluate the effectiveness of concomitant administration of hyaluronic acid and topical hyperbaric oxygen therapy (THOT) by a specifically designed medical device (vaginal natural oxygenation device, VNOD) in improving the...
Clinical Trial – ED90 for Hyperbaric Bupivacaine in Super Obese Parturients
The aim of this study is to determine the ED90 of hyperbaric intrathecal bupivacaine for the
super obese population undergoing cesarean section under a combined spinal epidural
technique.
Clinical Trial – ED50 and ED95 of Isobaric Bupivacaine for Post-Partum Bilateral Tubal Ligation
Spinal anesthesia is one of the preferred anesthetic techniques for post-partum bilateral
tubal ligation (PBTL). Bupivacaine is the most commonly used local anesthetic for neuraxial
anesthesia for post-partum tubal ligation. Typically, hyperbaric bupivacaine would be
injected into the spinal (intrathecal) space via a spinal needle; however, ongoing medication
shortages have resulted in limited availability on a local and national level. One proposed
alternative is isobaric bupivacaine; however, studies investigating its use for post-partum
bilateral tubal ligation are limited.
The purpose of this prospective study is to determine the minimal effective dose (ED50 and
ED95) of isobaric bupivacaine for adequate anesthesia during post-partum tubal ligation after
vaginal delivery.
A Case of Refractory Hemorrhagic Cystitis in which Bleeding Control was Finally Achieved by Cystectomy.
A 60-year-old man presented at our hospital with gross hematuria. He had been treated for nephrotic syndrome with cyclophosphamide and steroids since he was in his 20s. We detected diffuse hemorrhagic cystitis on cystoscopy and diagnosed him with cyclophosphamide-induced hemorrhagic cystitis. He was hospitalized due to clot retention. We treated him with blood transfusion for severe anemia and conducted continuous bladder irrigation. We performed hyperbaric oxygen therapy and transurethral electric coagulation, and increased the steroid dose. However, we could not control the hematuria. Finally, we performed cystectomy, and he is now well without hematuria. Although cystectomy is the final option, it is important to decide it in a timely manner because a delay decreases the quality of life.
Erratum: Effect of hyperbaric oxygenation therapy on post-concussion syndrome.
The present review evaluated the effect of hyperbaric oxygenation (HBO) therapy on post-concussion syndrome (PCS). Searches for publications from the earliest date possible up until the first week of 2016 were conducted using the electronic databases Cochrane, EBSCOhost, Embase, Ovid MEDLINE, PubMed and Web of Science. Additional trials were identified through reference list scanning. Randomized controlled trials assessing the effectiveness of HBO therapy in PCS were selected and tested for eligibility for inclusion in the present review.
Hypoxia and hyperbaric oxygen therapy: a review.
Abstract: Hypoxia causes a cascade of activity from the level of the individual down to the regulation and function of the cell nucleus. Prolonged periods of low oxygen tension are a core feature of several disease states. Advances in the study of molecular biology...
Clinical Trial – Low Dose Hyperbaric Bupivacaine and Dexmedetomidine as an Adjuvant, Caesarean Section
The aim of this study is to evaluate the effectiveness of low dose scheme with
dexmedetomidine as an adjuvant. Taking in consideration optimum intraoperative surgical
conditions, best post-operative pain free experience, and more stable hemodynamic.
Cerebral Venous Air Embolism: A Rare Phenomenon.
Abstract: Cerebral venous air embolism (CVAE) is an extremely rare phenomenon. Most reports of cerebral air embolism focus on the arterial territory, and consequently CVAE has remained poorly understood, especially regarding its pathophysiology and treatment. The...
BK Virus Associated Haemorrhagic Cystitis. A systematic review of current prevention and treatment strategies.
Abstract: BK virus is a major cause of late onset haemorrhagic cystitis in patients undergoing Haematopoietic Cell Transplantation (HCT). The evidence for the management of BK Virus Associated Haemorrhagic Cystitis (BKV-HC) is limited. Much of the published data...