HBOT Research

Clinical Trial – Fascia Iliaca Block for Anesthesia in Lower Limb Thromboembolectomy

The fascia iliaca block (FIB) is an anterior approach to block the lumbar plexus. It
disturbed mainly to the anterior region of the thigh by blocking the femoral nerve (LFC) and
the lateral femoral cutaneous nerve. Moreover, FIB may possibly be extended to the obturator,
ilioinguinal, genitofemoral, lateral cutaneous nerve of the thigh and over the psoas muscle
but, rarely reaches the lumbar plexus.

The fascia iliaca compartment could be detected by bony landmarks palpation and the loss of
resistance technique. Feeling two tactile ”pops” due to loss of resistance occurred during
the needle passage through the fascia lata and the fascia iliaca. Ultrasound (US) guidance of
FIB will increase the success rate and the efficacy of sensory blockade by decreasing the
needed local anesthetic amount.

Radiation-induced skin reactions: mechanism and treatment.

Radiotherapy (RT) is a major treatment for malignant tumors. The latest data show that >70% of patients with malignant tumors need RT at different periods. Skin changes can be experienced by up to 95% of patients who underwent RT. Inflammation and oxidative stress (OS) have been shown to be generally associated with radiation-induced skin reactions (RISRs). Inflammatory response and OS interact and promote each other during RISRs. Severe skin reactions often have a great impact on the progress of RT. The treatment of RISRs is particularly critical because advanced RT technology can also lead to skin reactions. RISRs are classified into acute and chronic reactions.

The Effect of a 300 mBar Increase in Barometric Pressure on Digital Microcirculation in Healthy Subjects Exposed to High Altitude: Is the Use of a Portable Hyperbaric Chamber to Treat Frostbite and/or Hypothermia in the Field Indicated? (Flow_Pulse Study).

Abstract: Savina, Yann, Sandra Leal, Pascal Zellner, François Becker, Monica Piris, and Emmanuel Cauchy. The effect of a 300 mbar increase in barometric pressure on digital microcirculation in healthy subjects exposed to high altitude: Is the use of a portable...

Hyperbaric oxygen combined with 5-aminolevulinic acid photodynamic therapy inhibited human squamous cell proliferation.

he photodynamic therapy (PDT) depends on the presence of molecular oxygen. Thus, the efficiency of PDT is limited in anoxic regions of tumor tissue and vascular shutdown. It is reported the use of hyperbaric oxygen (HBO) may enhance the efficiency of PDT. However, there are rarely studies about utilizing HBO plus PDT for treatment with human squamous cell carcinoma (SCC). Therefore, this study aimed to investigate and compare the therapeutic effect of combined therapy and PDT alone treatment. Multiple cellular and molecular biology techniques were used in the current study such as CCK-8, western blotting, flow cytometry, MDC staining and immunofluorescence assay.

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