Isobaric Ropivacaine 15 mg Versus Hyperbaric Bupivacaine 12.5 mg for Spinal Anesthesia in Geriatric Patients Undergoing Total Knee Arthroplasty
Description:
52 patients physical status II-III according to the American Society of Anesthesiologists
classification aged 65 years and above of average height, and scheduled for total knee
replacement under spinal anesthesia.
Patients were randomly assigned into two equal groups of 26 patients each according to the
type of local anesthetic injected in the subarachnoid space , Group I : patients who received
an intrathecal injection of 12.5 mg of 0.5% hyperbaric bupivacaine , Group II: patients who
received an intrathecal injection of 15 mg of 0.5% ropivacaine.
The investigators compared both groups as regards the extent and duration of sensory and
motor block and hemodynamics including heart rate (HR) , non invasive mean arterial blood
pressure (MAP) and respiratory depression.
Condition:
Total Knee Arthroplasty in Geriatric Patients
Treatment:
Hyperbaric bupivacaine
Start Date:
January 2013
Sponsor:
Mohamed Sayed Mohamed Abbas
For More Information:
https://clinicaltrials.gov/show/NCT02764723