Abstract:
Intrathecal ketamine has been studied extensively in animals, but rarely in humans. Intrathecal dexmedetomidine prolongs the duration of spinal anesthesia. To investigate the efficacy and safety of intrathecal dexmedetomidine, ketamine, or both when added to bupivacaine for postoperative analgesia in major abdominal cancer surgery. Double-blinded, randomized, controlled trial. Academic medical center.
Mohamed, El-Rahman, Fares, , , , , , (2016). Intrathecal Dexmedetomidine, Ketamine, and their Combination Added to Bupivacaine for Postoperative Analgesia in Major Abdominal Cancer Surgery. Pain physician, 2016 Jul;19(6):E829-39. https://www.ncbi.nlm.nih.gov/pubmed/27454273