News & Research
Hyperbaric Oxygen Therapy has been used for the better part of two centuries. Search our arhives below for past HBOT news and research or scroll down for the latest.
The Latest HBOT News & Research
Hyperbaric oxygen-associated seizure leading to stroke.
Oxygen toxicity seizures are a well-known complication of hyperbaric oxygen treatment (HBOT). Until now, there have not been any reported cases of an acute ischaemic event (stroke) as the result of a HBOT-associated oxygen toxicity seizure. We report an event in which a seizure and stroke occurred together and consider that the stroke may have been caused by seizure-induced demand ischaemia. This challenges the generally held view that oxygen toxicity seizures in the clinical hyperbaric setting are benign. A discussion of the literature on the subject of seizure-induced brain injury is included. Risk factors for cerebrovascular disease should be taken into consideration in determining treatment pressures for HBOT, as reducing pressure reduces seizure risk.
Clinical Trial – Epidural Steroids With Intrathecal Nalbuphine for Lower Abdominal Oncologic Surgery
Intraoperative pain, nausea, vomiting, hypotension, bradycardia are known side effects during
lower abdominal surgery under spinal anesthesia, Time to 2 segment regression of sensory
block and duration of effective analgesia prolonged with intrathecal (IT) 0.4 mg nalbuphine &
IT 0.8 mg nalbuphine, but the incidence of side-effects was significantly higher with IT 0.8
mg nalbuphine compared with (IT) 0.4 mg nalbuphine.
Proliferative retinopathy during hyperbaric oxygen treatment.
Abstract: A 43-year-old male with type 2 diabetes mellitus, treated with insulin for 28 years and with an HbA1c of 7.9% six months prior, suffered from bilateral plantar ulcers refractory to specialised wound care. He underwent a planned 40...
Associations of Plasma Nitrite, L-Arginine and Asymmetric Dimethylarginine with Morbidity and Mortality in Patients with Necrotizing Soft Tissue Infections.
Abstract: The nitric oxide system could play an important role in the pathophysiology related to necrotizing soft tissue infection (NSTI). Accordingly, we investigated the association between plasma nitrite level at admission and the presence of...
Hyperbaric oxygen in the treatment of acute retinal artery occlusion.
Abstract: Acute retinal artery occlusion (ARAO) is a major cause of sudden, painless visual loss, often leaving no useful vision in the affected eye. Its incidence is cited at 0.85 per 100,000 persons per year but may be higher because of...
Cervical Necrotizing Fasciitis of Odontogenic Origin and Hyperbaric Oxygen Therapy.
Abstract: Necrotizing fasciitis (NF) is an infection of the soft tissues pathology with high mortality that spreads through the fascial planes and rarely seen in head and neck region. The cause of infection is often odontogenic problems....
Is There a Place for Ozone Therapy in Patients with Heart Failure?
Abstract: Clavo, Eltobgy, Caballero, Abad, Rodríguez-Esparragón, Santana-Rodríguez, , , (2017). Is There a Place for Ozone Therapy in Patients with Heart Failure? Cardiovascular toxicology, 2017...
Clinical Trial – The RESPOND Registry
The RESPOND Registry is an observational study to assess the impact of PuraPly™ AM on the
management of wounds in real world clinical settings; no experimental intervention is
involved.
Hyperbaric Oxygen Therapy after Acute Thoracic Spinal Cord Injury: Improvement of Locomotor Recovery in Rats.
The aim of this study was to analyze the effectiveness of hyperbaric therapy (HT) using mild and moderate models of spinal cord injury (SCI). SCI can cause permanent impairment with socioeconomic consequences. The motor deficit occurs by two mechanisms: destruction of neuronal cells and local inflammatory response, resulting in hypoxia. HT acts by increasing oxygen in the injured area. Thoracic laminectomy was performed in 72 female Wistar rats. The MASCIS impactor was used at 12.5 mm (n = 35) and 25 mm (n = 35) of height to perform, respectively, mild and moderate SCI. Muscle strength was assessed through the Basso, Beattie, and Bresnahan scale (BBB) on days 1, 7, 14, 21, and 28 after SCI. The animals were randomized into five subgroups with seven animals each: (1) control group had SCI without HT; (2) HT 30 minutes after SCI; (3) HT 30 minutes after SCI and daily for 7 days; (4) HT 12 hours after SCI; and (5) HT 12 hours after SCI and daily for 7 days. HT was performed at 2.5 atm for 1 hour.