News & Research
Hyperbaric Oxygen Therapy has been used for the better part of two centuries. Search our arhives below for past HBOT news and research or scroll down for the latest.
The Latest HBOT News & Research
Perfluorocarbon emulsions radiosensitise brain tumors in carbogen breathing mice with orthotopic GL261 gliomas.
Abstract: Tumour hypoxia limits the effectiveness of radiation therapy. Delivering normobaric or hyperbaric oxygen therapy elevates pO2 in both tumour and normal brain tissue. However, pO2 levels return to baseline within 15 minutes of stopping...
Co-administration of tissue plasminogen activator and hyperbaric oxygen in ischemic stroke: a continued promise for neuroprotection.
Abstract: Intravenous recombinant tissue-type plasminogen activator (r-tPA, alteplase) remains the recommended therapy for acute ischemic stroke. However, several factors are limiting its practical use. It makes it urgent for us to search more...
Co-administration of tissue plasminogen activator and hyperbaric oxygen in ischemic stroke: a continued promise for neuroprotection.
Abstract: Intravenous recombinant tissue-type plasminogen activator (r-tPA, alteplase) remains the recommended therapy for acute ischemic stroke. However, several factors are limiting its practical use. It makes it urgent for us to search more...
A technical diving-related burns case: treatment in a remote location.
Abstract: Injuries suffered as a result of a rebreather oxygen explosion and fire occurred to a diver on vacation in the island state of Chuuk, Micronesia. The medical and logistical management of the diver in a remote location are described. The...
Clinical Trial – Spinal Marginally Hyperbaric Ropivacaine for Cesarean Delivery
BACKGROUND: One previous study has confirmed that the marginally hyperbaric solutions of
bupivacaine can maintain good quality of anesthesia and get a more steadily hemodynamic
status than commonly hyperbaric solutions, some authors confirmed the plain ropivacaine for
cesarean section have a higher failure rate and commonly hyperbaric solutions of ropivacaine
have a higher incidence of side reaction. It is unclear what the efficacy of spinal
marginally hyperbaric ropivacaine for elective cesarean delivery.We hypothesized that the
marginally hyperbaric ropivacaine will get a similar efficacy to commonly hyperbaric
solutions but a more steadily hemodynamic status.
OBJECTIVE In this prospective, randomized, double-blinded study, Investigator will compare
the clinical efficacy and adverse effect of spinal anesthesia with commonly hyperbaric and
marginally hyperbaric ropivacaine for elective cesarean delivery.
Main outcome measures: The maximum cephalad sensory block level; the change of continuous
cerebral oxygen desaturation (ScO2) over time; the incidence of hypotension and nausea and
vomiting; the change of invasive arterial pressure; the consumption of ephedrine; the
incidence of shivering; the onset time to T8 dermatome; the quality of anesthesia (efficacy
of motor block and sensory block)
Clinical Trial – Comparison of Regional Anesthesia Techniques After Total Knee Arthroplasty
Comparison of continuous adductor canal block to continuous femoral nerve block in patients
after total knee arthroplasty.
All patients will be anesthetized with spinal anesthesia. Continuous infusion of ropivacaine
with a catheter implemented to the adductor canal or next to the femoral nerve.
The observed goals: pain intensity, the beginning and quality of rehabilitation.
Clinical Trial – Evaluation of Hyperbaric Oxygen Therapy on Wound Healing Following Management of Soft Tissue Sarcoma With Neo-Adjuvant Radiation and Surgical Resection
A prospective, randomized investigation with appropriate power would determine whether or not
postoperative hyperbaric oxygen therapy improves wound healing in patients with soft tissue
sarcoma undergoing surgical resection with neo-adjuvant radiation therapy.
Clinical Trial – Hyperbaric Oxygen Therapy for Inflammatory Conditions of the Urinary Bladder
Pilot study to determine feasibility for treating patients with two chronic inflammatory
conditions of the urinary bladder: chronic interstitial cystitis and recurrent urinary tract
infections using a standardized hyperbaric oxygen treatment plan. Presently there are no good
treatments for these conditions and hyperbaric oxygen may be a safe and readily accessible
therapy as it has proven successful an another type of chronic inflammatory condition of the
urinary bladder known as "radiation cystitis". The study will determine if patients will
consider this an acceptable treatment for their conditions and that it is well tolerated.
Clinical Trial – Insulin Sensitivity During Hyperbaric Oxygen Compared to Hyperbaric Air
In a recent series of studies performed by our group, we have shown that exposure to
hyperbaric oxygen (HBO) leads to an increase in insulin sensitivity in male subjects with
type-2 diabetes (T2DM) and in obese and overweight men without diabetes. The aim of this
study is to investigate the relationship between pressure and oxygen in producing this
effect, specifically, is this effect measurable in hyperbaric air or is some higher pressure
of oxygen required?
Aims:
1. To determine whether the insulin sensitising effect of HBO is apparent in hyperbaric air
at the same pressure as HBO.
2. To examine mechanisms underpinning the increase in insulin sensitivity following HBO.
