News & Research
Hyperbaric Oxygen Therapy has been used for the better part of two centuries. Search our arhives below for past HBOT news and research or scroll down for the latest.
The Latest HBOT News & Research
Clinical Trial – GA/Spinal vs. GA/Spinal/NMB for Operative Repair of Hip Fracture
Surgical repair of hip fractures may be performed with various anesthetic techniques, but are
most commonly completed under general anesthesia (GA) or neuraxial anesthesia (NA). Numerous
prospective and retrospective studies demonstrate improved morbidity and mortality when NA is
used; however, many surgeons prefer the use of GA with neuromuscular blockade (NMB) due to
the perception of better operative conditions. This study aims to compare the operative
conditions obtained from the use of combined GA and spinal with NMB vs. the use of GA with
spinal without NMB. 84 patients will all receive a single shot spinal and GA and then will be
randomized to receive either NMB or placebo. The fracture reduction time will be measured.
Concussion Help in a Hyperbaric Chamber? Local Doctor Says Treatment Can Get Rid of Injury
HBOT for Conussions. An old and familiar piece of technology is being used in the northern suburbs for a whole new reason: to get rid of concussions. Chicago-area doctor Daphne Denham says, when it comes to acute concussions, typically those that...
A Prospective, Randomized, Blinded, Controlled Trial Comparing Transdermal Continuous Oxygen Delivery to Moist Wound Therapy for the Treatment of Diabetic Foot Ulcers.
Abstract: Worldwide, diabetic foot ulcers (DFUs) continue to exact a major burden on patients and health care providers. Although hyperbaric oxygen therapy is well-known as an adjunct option, less is known about the efficacy of transdermal...
Effect of hyperbaric air on endotoxin from Bacteroides fragilis strains.
Abstract: The aim of the project was to determine any effect of hyperbaric air on Bacteroides fragilis strains cultivated under hyperbaric conditions. Previously, it was hypothesized that there was a correlation between the presence of Bacteroides...
Clinical Trial – Prognosis and Treatment of Necrotizing Soft Tissue Infections: A Prospective Cohort Study
The investigators will analyze biomarkers related to the prognosis and treatment of
necrotizing soft tissue infections (NSTI). The focus will be on whether certain endothelial
and immune system biomarkers can function as markers of disease severity, mortality as well
as the effects of hyperbaric oxygen therapy (HBOT). Biomarkers will be measured upon
admission to an intensive care unit at Copenhagen University Hospital and during the
following 3 days.
Relationship between hyperbaric oxygen therapy and quality of life in participants with chronic diabetic foot ulcers: data from a randomized controlled trial.
Abstract: To investigate the effect of hyperbaric oxygen therapy on health-related quality of life (HRQoL) in participants with diabetes and chronic foot ulcers. Using data from a randomized controlled trial, we included 103 participants (49 in...
Hyperbaric oxygen for experimental intracerebral haemorrhage: Systematic review and stratified meta-analysis.
Abstract: Hyperbaric oxygen (HBO) is widely used in treating various neurological diseases. However, HBO for treatment of intracerebral haemorrhage (ICH) remains controversial, in either animal or clinical studies. Therefore, we conducted this...
Nonhealing Ulcers in Patients with Tophaceous Gout: A Systematic Review.
Abstract: To provide information from a review of the literature about chronic ulcers associated with tophaceous gout. This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an...
Clinical Trial – Oxygen as a Limiting Factor for Performing Multitasking
The Brain uses 20% of the total oxygen supply consumed by the entire body. Even though, less
than 10% of the brain is active at every given time, the brain utilizes almost all the oxygen
delivered. In order to perform different tasks or more than one task (multi-tasking), the
oxygen supply is shifted from one brain region to another, via modulation of blood perfusion.
The aim of the present study was to evaluate whether hyperbaric oxygen (HBO) environment,
with increased oxygen supply to the brain, will enable better performance of complex and/or
multiple activities.
Methods: a prospective, double blind randomized control, cross over trial including healthy
volunteers. Participants were asked to perform a cognitive task, a motor task and a
simultaneous cognitive-motor task (multi-tasking). Participants were randomized to perform
the tasks at 2 environments: (a) normobaric air (1ATA 21% oxygen) (b) HBO (2ATA 100% oxygen).
Two weeks later participants were crossed to the alternative environment. Blinding of the
normobaric environment was achieved in the same chamber with masks on while hyperbaric
sensation was simulated by increasing pressure in the first minute and gradually decreasing
to normobaric environment prior to tasks performance.