News & Research
Hyperbaric Oxygen Therapy has been used for the better part of two centuries. Search our arhives below for past HBOT news and research or scroll down for the latest.
The Latest HBOT News & Research
The NO-cGMP-PKG signal transduction pathway is involved in the analgesic effect of early hyperbaric oxygen treatment of neuropathic pain.
Abstract: Hyperbaric oxygen (HBO) has the potential to relieve neuropathic pain. The purpose of this study was to determine whether the NO-cGMP-PKG signaling pathway is involved in the analgesic effects of early hyperbaric oxygen treatment of...
Geraniol promotes functional recovery and attenuates neuropathic pain in rats with spinal cord injury.
Abstract: Geraniol, a plant-derived monoterpene, has been extensively studied and showed a wide variety of beneficial effects. The aim of this study was to investigate the therapeutic effect of geraniol on functional recovery and neuropathic pain...
Healing of spongiosus-cutaneous fistula with hyperbaric Oxygen Therapy (HBOT): a case report.
Abstract: We present a case of a spongiosus-cutaneous fistula in a 39-year-old man with recurrent episodes of cutaneous abscess in dorsal middle third penis (5 × 3 cm) treated with Hyperbaric Oxygen Therapy (HBOT). After emptying nodular abscess,...
Microangiography to Monitor Treatment Outcomes Following Severe Frostbite Injury to the Hands.
Abstract: Frostbite injury causes direct damage to tissues following exposure to temperatures below their freezing point causing tissue death potentially leading to serious amputations. After rewarming, a variety of treatment options have been...
Identifying and acting on potentially inappropriate care? Inadequacy of current hospital coding for this task.
Abstract: Recent Australian attempts to facilitate disinvestment in healthcare, by identifying instances of 'inappropriate' care from large Government datasets, are subject to significant methodological flaws. Amongst other criticisms has been the...
Use of epidermal skin grafts in chronic wounds: a case series.
Abstract: In stalled, chronic wounds, more aggressive and proactive wound closure efforts are needed. We describe adjunctive use of epidermal grafting in patients with chronic wounds. Wound bed preparation consisted of surgical necrotectomy or...
Clinical Trial – Hyperbaric Oxygenation (HBO) in Traumatic Spinal Cord Injury. (EOS) – Pilot Study
Hypothesis of the Study:
Based on the presented results, the investigator hypothesises that HBO preserves neurons that
are not irreversibly damaged (i.e. severed) during initial trauma, thus enabling regain of
their function. The investigator predicts that HBO treatment protects and enhances motor
function in initially paralysed regions, including improvement in function of the extremities
as well as recovery of urinary bladder control and bowel function.
Outline of the Proposed Study:
Within a prospective "proof of principle" trial, a total of 100 patients will be included.
Fifty patients will be recruited at the Division of Thoracic and Hyperbaric Surgery, Medical
University of Graz. In parallel, 50 control patients will be included at the Department of
Orthopaedics and Trauma, Paracelsus University Salzburg, Salzburger Landeskliniken (SALK),
Austria. Thereby, all patients that are admitted at the Medical University of Graz can be
treated and the enrolment of 50 patients into the treatment group can be implemented within
the outlined time frame. The active recruitment period is planned for three years. Both HBO
treated and control patients will undergo the same surgical and nonsurgical procedures. HBO
treatment will be started within 24 hours after the injury. A total of 21 consecutive daily
sessions will be applied, followed by routine rehabilitation programmes. By matching control
and HBO-treated patients, an evaluation of the treatment effect of HBO is possible. The
outcome will be evaluated by implementing the American Spinal Injury Association
(ASIA)-scores and magnet resonance (MR) imaging. Additionally, inflammatory and regenerative
blood markers will be analysed (neuroendocrine markers/neuro-transmitters: S100beta, Brain
Derived Neurotrophic Growth Factor [BDNF], Glial Fibrillary Acidic Protein [GFAP], Reactive
Oxygen Species (ROS), norepinephrine; array of pro- and anti-inflammatory cytokines and
chemokines).
Clinical Trial – Seated Time for 90% Incidence of Hypotension
The study will determine the 90% effective seated time after intrathecal injection of
hyperbaric bupivacaine to avoid hypotension in patients undergoing cesarean delivery.
Hyperbaric Oxygen Therapy: Exploring the Clinical Evidence.
Abstract: To provide information about hyperbaric oxygen therapy (HBOT), its mechanisms, indications and safe applications based on clinical evidence. This continuing education activity is intended for physicians, physician assistants, nurse...