News & Research
Hyperbaric Oxygen Therapy has been used for the better part of two centuries. Search our arhives below for past HBOT news and research or scroll down for the latest.
The Latest HBOT News & Research
Diagnostic work-up and specific causes of acute kidney injury.
Abstract: Acute kidney injury (AKI) is common in critically ill patients and associated with grim short- and long-term outcome. Although in the vast majority of cases AKI is multifactorial, with sepsis, shock and nephrotoxicity accounting for most...
Comparison of Different Treatment Methods for Idiopathic Sudden Sensorineural Hearing Loss.
Abstract: To evaluate the effectiveness of different therapies for idiopathic sudden sensorineural hearing loss and prognostic factors, and determine the most successful treatment according to the audiogram type and time from onset to treatment. A...
Hyperbaric Oxygen Pretreatment Improves Cognition and Reduces Hippocampal Damage Via p38 Mitogen-Activated Protein Kinase in a Rat Model.
To investigate the effects of hyperbaric oxygen (HBO) pretreatment on cognitive decline and neuronal damage in an Alzheimer’s disease (AD) rat model. Rats were divided into three groups: normal saline (NS), AD, and HBO+AD. In the AD group, amyloid β peptide (Aβ)₁₋₄₀ was injected into the hippocampal CA1 region of the brain. NS rats received NS injection. In the HBO+AD group, rats received 5 days of daily HBO therapy following Aβ₁₋₄₀ injection. Learning and memory capabilities were examined using the Morris water maze task. Neuronal damage and astrocyte activation were evaluated by hematoxylin-eosin staining and immunohistochemistry, respectively. Dendritic spine density was determined by Golgi-Cox staining. Tumor necrosis factor-α, interleukin-1β, and interleukin-10 production was assessed by enzyme-linked immunosorbent assay. Neuron apoptosis was evaluated by terminal deoxynucleotidyl transferase dUTP nick end labeling. Protein expression was examined by western blotting. HBO pretreatment improves cognition and reduces hippocampal damage via p38 MAPK in AD rats.
Efficacy of hyperbaric oxygen therapy in patients with radiation-induced rectal ulcers: Report of five cases.
Abstract: For decades, hyperbaric oxygen therapy has been considered a treatment option in patients with chronic radiation-induced proctitis after pelvic radiation therapy. Refractory cases of chronic radiation-induced proctitis include ulceration,...
Barriers to Nutrition Intervention for Patients With a Traumatic Brain Injury.
Abstract: Nutrition delivered to patients with a traumatic brain injury (TBI) is typically below prescribed amounts. While the dietitian plays an important role in the assessment and provision of nutrition needs, they are part of a...
Clinical Trial – Comparison of Hyperbaric Prilocaine With Chloroprocaine for Intrathecal Anaesthesia in Day Case Knee Arthroscopy
This study compares intrathecal 1% plain chloroprocaine with intrathecal 2% hyperbaric
prilocaine for patients undergoing ambulatory knee arthroscopy in terms of efficacy and side
effects
Clinical Trial – Hyperbaric Oxygen Therapy for Cognition in Diabetic Elderly at High Dementia Risk
An urgent need exists to identify effective interventions to arrest or reverse dementia and
cognitive loss at its earliest stages. The proposed pilot randomized clinical trial will
investigate the short and long-term effects of hyperbaric oxygen therapy on cognitive
functioning, cerebral blood flow, and glucose uptake in diabetic elderly with mild cognitive
impairment. and provide the basis for a large-scale multi-center study of hyperbaric oxygen
therapy effects on cognition in diabetes. The potential to preserve, or even enhance,
cognition in elderly at high risk of cognitive decline and dementia has major implications
for the affected individuals and their support systems that bear the social and financial
burdens of long-term caregiving.
Development of a Limb-Preservation Program.
Abstract: In the global scenario, as the prevalence of renal failure and diabetes increases, healing and limb preservation assume increasing clinical importance for patients and healthcare systems. Unfortunately, there continues to be variation in...
Effects of hyperbaric oxygen treatment on gastric cancer cell line SGC7901.
Abstract: Hyperbaric oxygen (HBO) has been previously identified as an effective adjunct treatment option for the management of brain injury, diabetic ulcers and chronic wounds. However, the roles of HBO as an adjunctive therapy for tumors remain...