News & Research
Hyperbaric Oxygen Therapy has been used for the better part of two centuries. Search our arhives below for past HBOT news and research or scroll down for the latest.
The Latest HBOT News & Research
Clinical Trial – Comparative Study of the Analgesic Effect of Spinal Anesthesia or Infiltration Anesthesia for Hemorrhoidectomy
Background and Objectives: Postoperative analgesia and early recovery are relevant for
hospital discharge after hemorrhoidectomy. This study investigated the postoperative
analgesic effect with local infiltration compared with spinal block.
Methods: This randomized study included 40 patients aged 18 to 60 years old. Local group (LG)
received local infiltration under general anaesthesia; spinal group (SG) received a
subarachnoid block. LG received general anaesthesia with propofol, atracurium and propofol
infusion as well as a local infiltration of 20 ml 0.75% ropivacaine. SG received 2 ml of 0.5%
hyperbaric bupivacaine. Analgesic supplementation was with 50µg of fentanyl for LG and 1%
lidocaine for SG. There were assessed: postoperative pain intensity, sphincter relaxation,
motor blockade of lower limbs, time to discharge, analgesic dose over 1 week and adverse
effects.
Clinical Trial – Spinal Anesthesia Associated With General Anesthesia in Coronary Artery Bypass
CONTEXT: In patients eligible for coronary artery bypass surgery, anesthesia should provide a
number of conditions that exceed the limits of cardiovascular stability, myocardial
protection and other organs. Moreover, the combination of general anesthesia and spinal
anesthesia lessens the homeostatic, metabolic, hormonal and immunosuppressive changes. The
goal of this research was to evaluate the consumption of fentanyl citrate in intra-operative
in Coronary Artery Bypass Grafting (CABG) surgery with cardiopulmonary bypass under spinal
anesthesia associated with general anesthesia.
METHODS: Clinical, prospective, randomized and double covered study, approved by the Research
Ethics Committee. Fifty-six patients candidates for CABG with CPB, after signing the Terms of
consent, were randomized and divided into two groups: GI – General and GII – General +
subarachnoid. General anesthesia was induced according to the weight of each patient and
maintenance with isoflurane and fentanyl. Spinal anesthesia was induced with 20 mg of 0.5%
hyperbaric bupivacaine and 200 mcg of morphine, the patient is placed in cephalo-position
slope of 45 degrees for 10 minutes in Group II. In the statistical study was performed using
the Mann-Whitney test; the level of statistical significance was set at 5%.
Deep tissue biopsy vs. superficial swab culture, including microbial loading determination, in the microbiological assessment of Skin and Soft Tissue Infections (SSTIs).
Abstract: Thirty-two patients affected by SSTIs including DFIs were enrolled between 2013 and 2014. Superficial swab was obtained before and after cleansing with sterile saline, and after ultrasonic debridement; deep tissue biopsy was obtained from...
Deep tissue biopsy vs. superficial swab culture, including microbial loading determination, in the microbiological assessment of Skin and Soft Tissue Infections (SSTIs).
Abstract: Thirty-two patients affected by SSTIs including DFIs were enrolled between 2013 and 2014. Superficial swab was obtained before and after cleansing with sterile saline, and after ultrasonic debridement; deep tissue biopsy was obtained from...
Amelioration of estrogen deficiency-induced obesity by collagen hydrolysate.
Abstract: Objectives: Menopausal transition with declining estrogen levels significantly affects the physiological properties of women and consequently contributes to a series of medical conditions, including obesity. Obesity is a crucial risk...
Pathophysiological and diagnostic implications of cardiac biomarkers and antidiuretic hormone release in distinguishing immersion pulmonary edema from decompression sickness.
Abstract: Immersion pulmonary edema (IPE) is a misdiagnosed environmental illness caused by water immersion, cold, and exertion. IPE occurs typically during SCUBA diving, snorkeling, and swimming. IPE is sometimes associated with myocardial injury...
Decreased FOXP3+ and GARP+ Tregs to neoadjuvant chemotherapy associated with favorable prognosis in advanced gastric cancer.
Abstract: Neoadjuvant chemotherapy (NACT) has been an increasingly used therapeutic strategy to improve the outcome of advanced gastric cancer (GC) over the past few decades. Lymphocytic infiltration has been reported to be associated with response...
Safety of transport and hyperbaric oxygen treatment in critically-ill patients from Padua hospitals into a centrally-located, stand-alone hyperbaric facility.
Abstract: Some patients admitted to the intensive care unit (ICU) might require repetitive hyperbaric oxygen treatment (HBOT) while receiving critical care. In such cases, the presence of a hyperbaric chamber located inside or near an ICU is...
Hyperbaric oxygen as an adjunctive therapy in treatment of malignancies, including brain tumours.
Hyperbaric oxygen (HBO) therapy is widely used as an adjunctive treatment for various pathological states, predominantly related to hypoxic and/or ischaemic conditions. It also holds promise as an approach to overcoming the problem of oxygen deficiency in the poorly oxygenated regions of the neoplastic tissue. Occurrence of local hypoxia within the central areas of solid tumours is one of the major issues contributing to ineffective medical treatment. However, in anti-cancer therapy, HBO alone gives a limited curative effect and is typically not applied by itself. More often, HBO is used as an adjuvant treatment along with other therapeutic modalities, such as radio- and chemotherapy.