News & Research
Hyperbaric Oxygen Therapy has been used for the better part of two centuries. Search our arhives below for past HBOT news and research or scroll down for the latest.
The Latest HBOT News & Research
Hyperbaric oxygen therapy as additional treatment in deep sternal wound infections – a single center’s experience.
Abstract: Deep sternal wound infection (DSWI) is one of the most serious complications after cardiac surgery procedures, observed in 5% of patients. Current standard medical therapy for DSWI includes antibiotics, surgical debridement, resuturing or...
Clinical Trial – The Diabetic Foot Ulcer Registry
This is an observational, longitudinal real world registry of diabetic foot ulcers created
from electronic health record data obtained in the course of clinical care. Data from
certified electronic health records transmit data as part of the requirement to share data
with a specialty registry under Objective 10 of Meaningful Use of an EHR.
Simulated Microgravity Disrupts Cytoskeleton Organization and Increases Apoptosis of Rat Neural Crest Stem Cells Via Upregulating CXCR4 Expression and RhoA-ROCK1-p38 MAPK-p53 Signaling.
Abstract: Neural crest stem cells (NCSCs) are a population of multipotent stem cells that are distributed broadly in many tissues and organs and are capable of differentiating into a variety of cell types that are dispersed throughout three germ...
Changes in vasomotion–effect of hyperbaric oxygen in patients with diabetes Type 2.
Abstract: To investigate vasomotion in diabetic patients who underwent sessions of hyperbaric oxygen (HBO2) therapy. Seventy-one patients with diabetes Type 2 and lower-extremity neuropathy were enrolled in a prospective matched case-control study....
Targeting hypoxia to overcome radiation resistance in head & neck cancers: real challenge or clinical fairytale?
Abstract: Tumor hypoxia is a major cause for failure of therapy in patients with inoperable head and neck cancers. Various anti-hypoxic treatment strategies (e.g. hyperbaric oxygenation, hypoxic cell sensitizers) have been tested in clinical trials...
Clinical Trial – Ondansetron vs Ondansetron Plus Dexamethasone for Relieving Intrathecal Morphine Side Effects After C-section
Background: Common adverse side effects related to the use of neuraxial opioids in the
obstetric population include nausea, vomiting, and pruritus. Serotonin (5-HT3) receptor
antagonists, in particular ondansetron, have been identified as possible antipruritic agents.
It was reported that dexamethasone plus ondansetron is more effective than ondansetron for
prevention of postoperative nausea and vomiting but no additional effect on treating
pruritus.
Objectives: The purpose of this study is to compare the effect of prophylactic ondansetron
versus ondansetron plus dexamethasone after cesarean section on pruritus and postoperative
nausea and vomiting (PONV).
Methods: A prospective randomized double blind study that will be conducted between June 2016
and June 2017. Patients will be randomly allocated into two groups. The first group will
receive 4 mg intravenous (IV) ondansetron while the other group will receive 4 mg IV
ondansetron plus 8 mg dexamethasone.
Mild Hyperbaric Oxygen Inhibits Growth-related Decrease in Muscle Oxidative Capacity of Rats with Metabolic Syndrome.
Abstract: We examined the effects of mild hyperbaric oxygen on the properties of the soleus muscle in rats with metabolic syndrome. Five-week-old metabolic syndrome (SHR/NDmcr-cp, cp/cp) rats were divided into normobaric (CP) and mild hyperbaric...
Hyperbaric Oxygen as Radiation Sensitizer for Locally Advanced Squamous Cell Carcinoma of the Oropharynx: A Phase 1 Dose-Escalation Study.
Abstract: To explore, in a dose-escalation study, the feasibility of hyperbaric oxygen (HBO) treatments immediately before intensity modulated radiation therapy in conjunction with cisplatinum chemotherapy for squamous cell carcinoma of the head...
Preoperative Glasgow Prognostic Score as additional independent prognostic parameter for patients with esophageal cancer after curative esophagectomy.
Abstract: Inflammation accelerates tumor growth followed by reduced survival in patients with cancer. The aim of this study was to evaluate the prognostic relevance of preoperatively increased levels of C-reactive protein (CRP) and the...
