News & Research
Hyperbaric Oxygen Therapy has been used for the better part of two centuries. Search our arhives below for past HBOT news and research or scroll down for the latest.
The Latest HBOT News & Research
The diabetic foot in 2015: an overview.
Abstract: In 2015, it can be said that the diabetic foot is no longer the Cinderella of diabetic complications. Thirty years ago there was little evidence-based research taking place on the diabetic foot, and there were no international meetings...
The diabetic foot in 2015: an overview.
Abstract: In 2015, it can be said that the diabetic foot is no longer the Cinderella of diabetic complications. Thirty years ago there was little evidence-based research taking place on the diabetic foot, and there were no international meetings...
Variable use of amiodarone is associated with a greater risk of recurrence of atrial fibrillation in the critically ill.
Abstract: Atrial fibrillation is a common rhythm disturbance in the general medical-surgical intensive care unit. Amiodarone is a popular drug in this setting but evidence to inform clinical practice remains scarce. We aimed to identify whether...
Clinical Trial – Two Syringe Spinal Anesthesia Technique for Cesarean Section: A Simple Way to Achieve More Satisfactory Block and Less Hypotension
Background: Poor spinal anaesthesia block is common and is difficult to manage; so a
technique to minimize its incidence is advisable. Hypotension is the commonest problem with
spinal anesthesia. Multiple trials to prevent or combat hypotension using positional changes,
fluid therapy and the use of vasopressors were tried. However, the drug choice and mode of
administration as either bolus or infusion is still a matter of debate.
Objectives: To compare the outcome of spinal injection of hyperbaric bupivacaine and fentanyl
separately to standard injection of mixed fentanyl with hyperbaric bupivacaine.
Design: A randomized, controlled clinical trial.
Setting: Single medical center from 5/2013 to 10/2014.
Patients & Methods: 124 parturient scheduled for elective cesarean section (CS) were randomly
allocated into two groups, each 62 parturient: Group M received spinal anesthesia using 10 mg
bupivacaine 0.5% premixed with 25 µg fentanyl in the same syringe and Group S received 25 µg
fentanyl in one syringe and 10 mg bupivacaine 0.5% without barbotage in a second syringe.
Intravenous fluid co-load with 15 ml/kg warm lactated ringer solution was started as fast
drip during, and continued after spinal anesthesia.
Patients were monitored for hemodynamic parameters, time of sensory onset and height of
maximum sensory block, lower limb motor blockade was scored using modified Bromage scale and
the frequency of side effects.
Clinical Trial – Intrathecal Opioid Study
This is an interventional drug trail to evaluate the effect of different intrathecal opioids
on post-operative pain experiences in women who have undergone caesarean section surgery.
Hyperbaric oxygen therapy for wound care.
Abstract: To describe the most common types of wounds indicated for hyperbaric oxygen therapy and the results. Cross-sectional study at a Hyperbaric Centre in the city of Salvador, Bahia, Brazil. The medical records of 200 patients treated with...
Clinical Trial – Cryotherapy and Doppler in Inflammatory Rheumatic Diseases
The primary aim of the study is to evaluate the effects of two local cryotherapy (ice or cold
gas) applications on arthritic knees.
Evaluation criteria (before/after treatment):
– synovial power-Doppler semi-quantitative score
– pain VAS (mm)
– cytokine levels in synovial fluid
– leukocyte count in synovial fluid
Clinical Trial – Pancreaticoduodenectomy With or Without Preoperative Hyperbaric Oxygen Therapy
The primary objective of this study is to assess the safety, tolerability and toxicity of
preoperative HBOT in patients undergoing a pancreaticoduodenal resection for premalignant and
malignant tumors of the common bile duct, periampullary and duodenum.
Clinical Trial – Subarachnoidal Anesthesia: Dexmedetomidine vs Fentanyl Plus Hyperbaric Bupivacaine for Lower Abdomen Surgery
Dexmedetomidine, highly selective agonist for alpha-2 receptors, enhances the sensory and
motor block with prolonged postoperative analgesia without hemodynamic compromise.
OBJECTIVE: To evaluate effects of dexmedetomidine vs fentanyl with hyperbaric bupivacaine
spinal anesthesia for lower abdominal surgeries.
METHODS: double-blind, randomized, American Society Anesthesiologist classification (ASA) : I
– II, 18-65 years. F group (23 patients) received 25 mcg fentanyl, Group D (27 patients), 10
mcg dexmedetomidine with 12.5 mg hyperbaric bupivacaine . 0,02mgrs morphine / kg
intravenously if EVA≥4was administered in postoperative period. Hemodynamic variables and O2
saturation intraoperatively was recorded, EVA every 4 hours, side effects, sensory block,
motor, sedation and peripheral neurological manifestations of toxicity.