News & Research
Hyperbaric Oxygen Therapy has been used for the better part of two centuries. Search our arhives below for past HBOT news and research or scroll down for the latest.
The Latest HBOT News & Research
Hyperbaric Oxygen Therapy for Alzheimer’s Disease.
Recent studies indicate that hyperbaric oxygen therapy (HBOT), a well-established therapy for decompression illness, could be a potential therapy for Alzheimer’s disease (AD). However, due to oxygen toxicity i.e., increased oxidative stress implicated in HBOT, the risk and benefit of HBOT for AD patients need to be further assessed clinically.
Modelling of ciprofloxacin killing enhanced by hyperbaric oxygen treatment in Pseudomonas aeruginosa PAO1 biofilms.
Abstract: In chronic lung infections by Pseudomonas aeruginosa (PA) the bacteria thrive in biofilm structures protected from the immune system of the host and from antibiotic treatment. Increasing evidence suggests that the susceptibility of the...
Ulcerated Necrobiosis Lipoidica.
A 23-year-old Caucasian female, with type I diabetes mellitus, presented with a 7-month history of two painful yellowish-red plaques with ulcerated centre in the left leg. A diagnosis of ulcerated necrobiosis lipoidica (NL) was made and she was started on pentoxifylline 400 mg tid and tacrolimus ointment 0.1%. After four months of treatment with no improvement, the patient was proposed for hyperbaric oxygen therapy (HBOT). Overall, she received a total of 30 sessions of HBOT, after which the wounds healed completely. There have been no recurrences in the 14 months following resolution.
Clinical Trial – Effect of Different Types of Anesthesia on Perioperative Brain Natriuretic Peptide Levels in Parturient Cardiac Patient Undergoing Elective Cesarean Section
comparing the effect of general anesthesia versus spinal anesthesia on brain natruretic
peptide hormone levels preoperatively and postoperatively in parturient cardiac patient
undergoing cesarean section
Clinical Trial – Hyperbaric Oxygen Therapy for Adult Onset Post Traumatic Stress Disorder
Posttraumatic stress disorder (PTSD) is the long term effect of severely distressing
traumatic event characterized by intrusive thoughts, nightmares, and avoidance. Brain imaging
of PTSD patients demonstrate alterations in regional brain perfusion, with stunned,
hypoperfused regions. Those brain-biological pathologies may be responsible for the limited
success rate of currently available interventions.
During the last years data regarding Hyperbaric Oxygen Therapy (HBOT) induced neuroplasticity
accumulated. A number of studies in traumatic brain injury, cerebrovascular attacks, and
fibromyalgia have presented evidence of improved perfusion and recovery of metabolic brain
tissues, accompanied by clinical improvement under HBOT even years after the acute insults.
Considerable evidence supports potential benefit of HBOT on PTSD, however, no clinical trial
was done on this pure PTSD population. The aim of the proposed study is to examine hyperbaric
oxygen therapy as a treatment for PTSD. Advanced brain imaging and functional analysis tools
will be used to evaluate treatment’s effect.
Carbon Monoxide Poisoning: Pathogenesis, Management, and Future Directions of Therapy.
Abstract: Carbon monoxide (CO) poisoning affects 50,000 people a year in the United States. The clinical presentation runs a spectrum, ranging from headache and dizziness to coma and death, with a mortality rate ranging from 1 to 3%. A significant...
Successful treatment of hepatic gas gangrene by open drainage: A case report and review of the Japanese literature.
Abstract: Liver gas gangrene is rare and has a low prognosis. This case, reports a successful treatment of hepatic gas gangrene using an open drainage technique, followed by antibiotics and hyperbaric oxygen therapy (HBO). An 82-year-old male with...
A Novel Approach to Estimate ROS Origination by Hyperbaric Oxygen Exposure, Targeted Probes and Specific Inhibitors.
Abstract: Reactive oxygen species (ROS) are considered fundamental in various physiological/pathophysiological processes and prevention/treatment measures such as hyperbaric oxygen (HBO) therapy. In this study, the origination of ROS in human...
Using advanced wound care and hyperbaric oxygen to manage wound complications following treatment of vulvovaginal carcinoma.
Abstract: Postoperative management of patients with vulvar cancer is associated with a high incidence of poor wound healing and radiation -induced late tissue necrosis. This case series demonstrates the impact on wound healing with the use of...