Abstract:

Migraine and cluster headaches are severe and disabling. Migraine affects up to 18% of women, while cluster headaches are much less common (0.2% of the population). A number of acute and prophylactic therapies are available. Hyperbaric oxygen therapy (HBOT) is the therapeutic administration of 100% oxygen at environmental pressures greater than one atmosphere, while normobaric oxygen therapy (NBOT) is oxygen administered at one atmosphere. To assess the safety and effectiveness of HBOT and NBOT for treating and preventing migraine and cluster headaches. We searched the following in May 2008: CENTRAL, MEDLINE, EMBASE, CINAHL, DORCTIHM and reference lists from relevant articles. Relevant journals were hand searched and researchers contacted. Randomised trials comparing HBOT or NBOT with one another, other active therapies, placebo (sham) interventions or no treatment in patients with migraine or cluster headache.

Bennett, French, Schnabel, Wasiak, Kranke, , , , (2008). Normobaric and hyperbaric oxygen therapy for migraine and cluster headache. The Cochrane database of systematic reviews, 2008 Jul;(3):CD005219. https://www.ncbi.nlm.nih.gov/pubmed/18646121