HBOT Conversations:
Dr. Jay Stevens
Optimizing Health & Longevity
Dr. James “Jay” Stevens is the Medical Director of Extivita-RTP. He earned a Bachelor of Arts in Zoology from UNC-Chapel Hill and a Doctor of Medicine from East Carolina University School of Medicine. He completed a Family Practice Residency at the Fairfax Family Practice Program at the Medical College of Virginia and the first Sports Medicine Fellowship at the University of North Carolina, Chapel Hill in 1991. He is Board Certified in both Family Practice and Anti-aging Medicine. He also holds a Certificate of Added Qualification in Sports Medicine. In 2003 he founded Carolina Family Practice & Sports Medicine with locations in Cary, Raleigh, and Holly Springs, NC. He has served as the Team Physician for the National Hockey League’s 2006 Stanley Cup Champion Carolina Hurricanes since their arrival in 1997. He also serves as Company Physician for the Carolina Ballet.
Watch the Podcast
Dr. Jay Stevens, Medical Director at Extivta, returns to HBOT News Network to discuss ways to optimize your health & longevity. In addition to being the Medical Director at Extivita, Dr. Stevens is also the Medical Director & Provider for the Cary, NC location of Essential Health. Essential Health has many locations across the country.
We are lucky to have Dr. Stevens here to share the insightful data and information he has come across over the course of his career.
Dr. Stevens starts by explaining that there is in fact a difference between someone’s health span and life span. Health span can be defined or looked at by how long can someone live before they succumb to disease? While, life span is more along the lines of quality of life, and wanting to live as long as possible. With life span, a person wants to keep the body as young, disease-free and as healthy as possible. This is where longevity fits in, because it ultimately is the desire to achieve the longest life span possible. But, he reminds us that functional medicine can never exist without conventional medicine. They both play a part in someone’s longevity and keeping diseases away.
Yet, how exactly does Hyperbaric Oxygen Therapy play a part in a person’s longevity goals? Dr. Stevens states that he sees HBOT as elegant and simplistic; because to create energy, we require a nutrient and oxygen. It’s as simple as that. But, our environments keep mucking that process up — toxins, poor diet, too much sugar, etc. We must look at Hyperbaric Oxygen Therapy as a mechanism to improve cellular energy production. He further explains that when we focus on optimizing everything about the cell lifestyle and then apply oxygen, we have a recipe to achieve the best outcome in energy production. But, why is energy production so important for longevity?! Because energy production in your immune system predicts how your immune system will function – more energy production and your immune system is boosted to preform better, thus optimizing the chances of keeping disease and illness away.
The topic of the immune system leads us into a discussion on immunosenescence and why it is so important. Dr. Stevens explains that ultimately, the longevity of our lives is predicted by our immune system. Thankfully Hyperbaric Oxygen Therapy is known to slow down the rate of decline in an aging immune system, and increase our body’s ability to regenerate stem cells.
Dr. Stevens again touches on the power of extended fasting, and why it plays such an important role in optimal health & longevity.
Dr. Stevens starts by explaining that there is in fact a difference between someone’s health span and life span. Health span can be defined or looked at by how long can someone live before they succumb to disease? While, life span is more along the lines of quality of life, and wanting to live as long as possible. With life span, a person wants to keep the body as young, disease-free and as healthy as possible. This is where longevity fits in, because it ultimately is the desire to achieve the longest life span possible. But, he reminds us that functional medicine can never exist without conventional medicine. They both play a part in someone’s longevity and keeping diseases away.
Yet, how exactly does Hyperbaric Oxygen Therapy play a part in a person’s longevity goals? Dr. Stevens states that he sees HBOT as elegant and simplistic; because to create energy, we require a nutrient and oxygen. It’s as simple as that. But, our environments keep mucking that process up — toxins, poor diet, too much sugar, etc. We must look at Hyperbaric Oxygen Therapy as a mechanism to improve cellular energy production. He further explains that when we focus on optimizing everything about the cell lifestyle and then apply oxygen, we have a recipe to achieve the best outcome in energy production. But, why is energy production so important for longevity?! Because energy production in your immune system predicts how your immune system will function – more energy production and your immune system is boosted to preform better, thus optimizing the chances of keeping disease and illness away.
The topic of the immune system leads us into a discussion on immunosenescence and why it is so important. Dr. Stevens explains that ultimately, the longevity of our lives is predicted by our immune system. Thankfully Hyperbaric Oxygen Therapy is known to slow down the rate of decline in an aging immune system, and increase our body’s ability to regenerate stem cells.
Dr. Stevens again touches on the power of extended fasting, and why it plays such an important role in optimal health & longevity.
Guest

Dr. Jay Stevens
Dr. James “Jay” Stevens earned a Bachelor of Arts in Zoology from UNC-Chapel Hill and a Doctor of Medicine from East Carolina University School of Medicine. He completed a Family Practice Residency at the Fairfax Family Practice Program at the Medical College of Virginia and the first Sports Medicine Fellowship at the University of North Carolina, Chapel Hill in 1991. He is Board Certified in both Family Practice and Anti-aging Medicine. He also has a Certificate of Added Qualification in Sports Medicine. In 2003 he founded Carolina Family Practice & Sports Medicine with locations in Cary, Raleigh, and Holly Springs, NC. He has served as the Team Physician for the National Hockey League’s 2006 Stanley Cup Champion Carolina Hurricanes since their arrival in 1997. He serves as Company Physician for the Carolina Ballet as well.
In 2009, his commitment to helping his patients create healthy lifestyles for long-term wellness, along with his desire to provide the highest quality health care services, motivated Dr. Stevens to establish Essential Health & Wellness (EHW). EHW offers its patients a comprehensive health care service tailored around their busy schedules with the goal of optimizing their performance and longevity.
In 2018, he continued this commitment to long-term wellness of his patients by becoming the Medical Director at Extivita RTP, a hyperbaric oxygen therapy facility with two, twelve seat treatment chambers in the Research Triangle Park, Durham, NC.
Dr. Stevens is also a Fellow in both the American Academy of Anti-Aging and Regenerative Medicine and the American Academy of Family Practice. He is a member of the American Medical Society of Sports Medicine and Hyperbaric Medicine International.
Dr. Stevens lives in Cary, NC with his wife, Dr. Patience Stevens. They have three sons Eric, James, and Timothy. He is passionate about surfing, triathlon and almost any form of exercise.
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Recent HBOT News
Clinical Trial – HBOT Late Radiation Tissue Injury
Background: Radiotherapy is a common treatment for many malignancies. Radiation-related
complications developing months or years after radiation treatment are known as late
radiation tissue injury (LRTI) and are estimated to effect 5%-15% of all long-term survivors
who have received radiation.
Hyperbaric oxygen therapy (HBOT) is a well established treatment of LRTI. Most of the studies
evaluating effect of HBOT on LRTI are focused on survival, resolution of tissue damage and
improvement in LENT-SOMA scale. Very few studies have addressed effect of HBOT on pain in
LTRI. Krahn and colleagues were the first to report the analgesic effect of HBOT in 3 cases
of refractory pain in oncological patients with radiation soft tissue injury. Other studies
showed significant improvement in pain intensity in patients with breast cancer and pelvic
malignancies treated with HBOT for LTRI. In patients that had developed radiation- induced
brachial plexopathy, HBOT elicited an increase in warm pain thresholds and a reduction in
lymphoedema. A prospective case study of 16 patients with gynecological cancer found no
changes with respect to pain and depression outcomes. A trial in patients with radiation
induced proctopathy showed that 75% of patients with rectal pain had some improvement,
although none experienced a complete resolution of pain symptoms.
There are several mechanisms by which HBOT may elicit analgesic effects. There is a growing
body of evidence that HBOT’s analgesic effect related to nitric oxide metabolism and
endogenous opioid secretion. Furthermore, the inhibition of tumor necrosis factor alph
(TNF-α), the production of substance P, and the modulation of serotonergic pathways have all
demonstrated a modification in the pain response following HBOT. In animal studies HBOT
decreased allodynia and hyperalgesia in different models of neuropathic and inflammatory
pain. The long lasting antinociceptive effect of HBOT was found to be dose-dependent in
non-injured tissues.
In human studies, HBOT decreased pain and edema and improved function in patients suffering
from the complex regional pain syndrome, and improved pain scores and range of motion in
patients with idiopathic femoral head necrosis. Women suffering from interstitial cystitis
demonstrated a reduction in pelvic pain following weeks and months of HBOT treatment. In
patients suffering from idiopathic trigeminal neuralgia HBOT produced a rapid reduction in
symptoms and these effects were lasting for 6 months following treatment. HBOT was also found
to be an effective treatment for cluster headaches and migraines and alleviated muscle and
bone pains in patients with myofascial syndrome, fibromyalgia, and biphosphonate-related
osteonecrosis of the jaw.
Based on the evidence presented above and HBOT’s known analgesic effect in many conditions,
the investigators designed this study with the objective to evaluate if HBOT reduces pain,
improves depression and impacts on patients quality of life in patients suffering from late
radiation tissue injury.
Study Design: Prospective observational study (n=300). Patients that have had radiation
therapy for malignancy, developed late radiation injury and suffer from chronic pain.
Clinical Trial – HBOT in Fibromyalgia
Fibromyalgia (FM) is a chronic pain condition affecting several millions of Canadians.
Although the etiology and pathophysiology are poorly understood, there is a well-recognized
association between muscular pain in fibromyalgia and muscular hypoperfusion, hypoxia,
abnormal muscle metabolism and oxidative stress. Currently there is no cure for FM.
Pharmacological and non-pharmacological strategies are directed to control symptoms such as
pain, fatigue, non-restorative sleep and depression.
Hyperbaric oxygen therapy (HBOT) is an intermittent inhalation of 100% oxygen in a hyperbaric
chamber at a pressure higher than 1 absolute atmosphere. Physiological effect of HBOT is
based on a dramatic increase in the amount of dissolved oxygen carried by the blood which
enables oxygenation of ischemic areas with compromised circulation. It also activates
oxidant-antioxidant system, stimulates angio- and neurogenesis, modulates inflammatory
response, induces brain neuroplasticity and possesses analgesic effect.
While some interventions offer benefit for some patients, additional treatment alternatives
are needed for patients with FM in whom currently available options are either ineffective or
poorly tolerated. Given its physiological effect, HBOT could be considered as a potential
therapy for treatment of underlying muscular hypoxia, optimizing oxidant- antioxidant system
and controlling FM symptoms. The results from this study could therefore provide new
information supporting the basic science underling the pathophysiology of this disease and
stimulate novel therapies for patients suffering with FM.
Thoracic spinal anesthesia is safe for patients undergoing abdominal cancer surgery.
Abstract: A double-blinded randomized controlled study to compare discharge time and patient satisfaction between two groups of patients submitted to open surgeries for abdominal malignancies using segmental thoracic spinal or general anesthesia. Open surgeries for...
