HBOT Conversations:
Laurie Anderson (Part 3)

Healing COVID with HBOT

 

Dr. Laurie is a Doctor of Pharmacy, and a graduate of the University of North Carolina – Chapel Hill (UNC-CH) School of Pharmacy and the Pharmacy Practice Residency Program at the University of California – San Francisco (UCSF).  Dr. Laurie spent many years in clinical practice, first as a neurosurgery clinical pharmacist at UCSF Medical Center and then as a general medicine and critical care clinical pharmacist at Duke Medical Center.  For the past 14 years Dr. Laurie has been working in industry, and is currently a safety scientist in early phase drug development, designing safety strategies for First Time in Human clinical trials.

Through her own journey navigating chronic illness, Dr. Laurie has explored and embraced many forms of alternative and non-traditional medicine to support her body for healing.  She has gravitated towards practitioners and modalities that treat the whole patient, with the mantra that tending to mind, body and spirit is the true key to lasting health.  Over the years, Dr. Laurie has discovered that this often leads to a ‘less is more’ approach. She discovered HBOT when she was struggling to heal from COVID, and now tells anyone who will listen about the power of oxygen and pressure.

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We continue Dr. Laurie Anderson’s HBOT News Network interview, diving in deeper to discuss our veteran population, does HBOT have a therapeutic index, and what is the research telling us about the HBOT industry.

Her interview has been released as a three part series. Part 1 and Part 2 has already been released with both focusing on her HBOT journey with COVID & Lyme Disease.

In Part 3 of Laurie’s podcast the conversation shifts.  It starts with the medical industry and the unfortunate “bad rap” that Hyperbaric Oxygen sometimes receives. Dr, Laurie refers to HBOT as a gift, so it’s truly unfortunate when the media focuses on the negative instead of the positive, influencing the public to not even try this life saving therapy.  Research trials are discussed, including the problems that the hyperbaric industry has identified in the sham, placebo and/or control group when researchers try to mimic HBOT with little pressure and they discover that everyone starts to improve. Those of us in this industry understand and effortlessly work to enlighten others that any amount of pressure is good and therapeutic.

The topic of our US military and the high rate of suicide among our service man and women arises.  Is there a solution to the veteran suicide epidemic our country is facing?  It appears there is.  di Girolamo speaks of Patriot Hyperbarics in Tulsa, and the success they have had treating veterans with Hyperbaric Oxygen Therapy.

“The Patriot Clinics in Tulsa treated some 500 veterans with PTSD, with donated money, donated chambers, and healed them. Most of them war-fighters, were in a bedroom, locked in the dark for years and years, like seven, ten years. And then they found Patriot Clinics and they got 40 treatments and then they got their executive function back. Some of them starting businesses. I saw videos of guys, you know, in the car on their way to the clinic on the first day and then on the 40th day, talking about their experience, it was just amazing.
There wasn’t some combined study about that. 500 souls were saved that didn’t commit suicide, they worked their way out of it.”

Dr. Laurie, who is a Doctor of Pharmacy, brings up an excellent point, and one that we’ve never discussed before on HBOT News.  We know that the FDA ultimately states that oxygen is a drug, and you are required to have a prescription for it.  But does Hyperbaric Oxygen have a therapeutic index like other drugs? And if so… how would a patient know they have reached the therapeutic index and how long is a patient at the therapeutic index? She explains it like this…

“If I apply this to drugs, like with a drug we would want to keep the level, generally, we try to keep the level of a drug in the blood inside the therapeutic index, right? So sometimes, depending on the half life of the drug, you can be in your therapeutic index by taking it once a day so you trickle up and down in between that therapeutic index. Some drugs have a shorter half life and you have to take it twice a day to stay in that therapeutic index.
So what keeps you in whatever is the defined therapeutic index, if that can be translated to oxygen therapy, you know, is it daily? Is it twice a day?”

di Girolamo wonders if in 20 years from now the industry will look back on this conversation and be shocked that we weren’t more focused on the therapeutic index. He stresses that the hyperbaric industry can’t even come together and decide the specific definition of hyperbaric oxygen, much less all these variables that Dr. Laurie has opened our eyes to. 

Dr. Laurie ends her time here with HBOT News stressing that for her HBOT healed her during a very sick time with COVID, and it helped her with many of the Lyme Disease symptoms she struggled with for years.  It worked for her, and she said it’s definitely worth a try to see if it can work for you.

 

Guests

Elena Schertz, NP

Dr. Laurie Anderson, Pharm.D.

Dr. Laurie is a Doctor of Pharmacy, and a graduate of the University of North Carolina – Chapel Hill (UNC-CH) School of Pharmacy and the Pharmacy Practice Residency Program at the University of California – San Francisco (UCSF).  Dr. Laurie spent many years in clinical practice, first as a neurosurgery clinical pharmacist at UCSF Medical Center and then as a general medicine and critical care clinical pharmacist at Duke Medical Center.  For the past 14 years Dr. Laurie has been working in industry, and is currently a safety scientist in early phase drug development, designing safety strategies for First Time in Human clinical trials.

Through her own journey navigating chronic illness, Dr. Laurie has explored and embraced many forms of alternative and non-traditional medicine to support her body for healing.  She has gravitated towards practitioners and modalities that treat the whole patient, with the mantra that tending to mind, body and spirit is the true key to lasting health.  Over the years, Dr. Laurie has discovered that this often leads to a ‘less is more’ approach.

When not working, Dr. Laurie is an avid gardener, ballroom dancer and traveler with her husband. Remaining curious and finding joy in every day are her super powers.

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Recent HBOT News

Clinical Trial – Hyperbaric Oxygenation in Athletes: Standard Versus Low Pressure

Currently, Hyperbaric Oxigen (HBO) is a widely used treatment for several conditions. There
are 14 indications for HBO, officially recognized by the Undersea and Hyperbaric Medical
Society (UHMS), but research is discovering other interesting applications.

HBO plays an important role in enhancing antioxidant defense mechanisms by increasing radical
oxygen species (ROS) and nitric oxide species (NOS). This controlled oxidative stress has
been shown to stop the vicious circle of inflammation – damage – hypoxia already seen in
several diseases. Increased neoangiogenesis has been demonstrated at pressures of 2
atmospheres absolute (ATA), while effects helping ischemic tissues need pressures between 2.5
and 2.8 ATA to develop.

During sports activities, metabolism generates waste products – mostly CO2, lactic acid, but
also ROS. HBO could be useful in modulating antioxidant mechanisms and helping cells in the
recovery after training and sportive competitions.

The authors hypothesize that:

1. HBO can reduce oxidative stress in healthy professional athletes

2. HBO can ameliorate the lactic acid clearance after a maximal exercise

3. HBO at low pressures (L-HBO at 1.45 ATA) is at least comparable to conventional HBO (at
2.5 ATA) in reducing oxidative stress and ameliorating lactic acid clearance after a
maximal exercise.

The Authors will include healthy athletes. These will be randomly assigned to a control
group, a L-HBO group, or a HBO group. The Authors will assess oxidative stress changes and
lactic acid clearance (testing it after a maximal exercise) before and after 20 L-HBO/HBO
treatments, and after 2 months after the end of treatments.

Clinical Trial – Hyperbaric Oxygen Therapy Compared to Pharmaceutical in Fibromyalgia With Emotional Trauma

The investigators have previously studied the efficacy of hyperbaric oxygen therapy (HBOT) as
a treatment for Fibromyalgia syndrome (FMS) in a prospective, active control, crossover
clinical trial. The results demonstrated significant amelioration of all FMS symptoms, with
significant improvement in life quality; furthermore, the investigators were able to
demonstrate significant neuroplasticity on SPECT imaging, with a decrease of the
hyperactivity in posterior regions and elevation of the reduced activity in frontal areas.

In this study, the investigators intend to both repeat and expand the investigator’s previous
findings, treating FMS patients with history of emotional trauma with HBOT, while performing
an extensive of evaluation both before and after treatment.

In the current study, the investigators plan to compare HBOT to current standard of care of
FMS (pharmacological and non – pharmacological).