In this Research Rundown we examine a TBI HBOT study that gets two thumbs up from our host, Edward diGirolamo. TBI (Traumatic Brain Injuries) is one of the leading causes of death and disability in the general population, with 25% of patients experiencing PCS (post-concussion syndrome) symptoms that last over 6 months.
Highlights:
- The study started with 264 participants and concluded with 154 participants; this is important as it revealed 110 participants were removed from the study for factors that could skew the results in a positive or negative way.
- HBOT was found effective despite the treatment being started in late, chronic stages of post-concussion syndrome.
- The study presents clean and organized data, such as percentage of improvements based on the severity of the TBI.
- Memory and attention showed an over 44% increase in severe TBI patients, with other cognitive markers also showing impressive numbers in all categories for each TBI group.
Mean changes of post-HBOT compared with pre-HBOT across the different TBI severities.
Mean changes of post-HBOT compared with pre-HBOT for the entire cohort.
The mean relative change in Broadmann areas post hyperbaric oxygen therapy for the entire study cohort.
Imaging findings in the severe traumatic brain injury group
TBI Patient Flowchart for HBOT
Cognitive functions correlated with Brodmann areas.
Cognitive functions correlated with Brodmann areas.
Read the Full Paper:
Hadanny, Abbott, Suzin, Bechor, Efrati (2018). Effect of hyperbaric oxygen therapy on chronic neurocognitive deficits of post-traumatic brain injury patients: retrospective analysis. BMJ open, 2018 Sep;8(9):e023387. https://www.ncbi.nlm.nih.gov/pubmed/30269074