Clinical Trial – Outcome Following Carbon Monoxide Poisoning in Children

Carbon monoxide poisoning is common. Many adults with CO poisoning have long-term, even
permanent brain injury following poisoning. However, very little is known about the long-term
outcome of children with carbon monoxide (CO) poisoning. In this study we plan to perform
cognitive (thinking) and vestibular (balance) testing in children (ages 6 to 16)at 6 weeks
and 6 months following CO poisoning.

At the 6-week visit, if the child and parents agree, we will ask each child to provide a DNA
sample by one of three methods: mouthwash, spit collection, or swabbing the inside of the
child’s cheek. Each child’s DNA will be analyzed for genes that are known to affect outcome
following brain injury.

Hyperbaric Autism Treatment Shows Possible Promise

To battle her son’s autism, Kazuko Curtin did more than look into a treatment — she started a clinic for it. Twelve years ago, Curtin was told by doctors that her son had autism. In subsequent years, while attending conferences, she heard about treatment...

Clinical Trial – A Clinical Trial of the Clinical Effects of Hyperbaric Oxygen Therapy in Thai Autistic Children

Autism is a developmental and behavioral pattern which includes the triad of impairments, 1.
social interaction 2. social communication 3. imagination. Inevitable difficulties in the
treatment, managing and handle with autistic children are the main problems. Their memories
are seemingly in picture or photo records, which are difference from normal population. There
are many concepts but no concise in causative factors, including useful treatments, useless
and prolong remaining in many studies.

HBOT (Hyperbaric Oxygen Therapy) is a quite modern treatment in Thailand for nitrogen
imbalance (decompression sickness syndrome or Caisson disease). How can we apply it to treat
the autism? A hypothesis shows evidence that neurons surrounding the permanently damaged
epicenter of injury can be reactivated with increased oxygen. Oxygen exists in the blood in
two forms, combined with hemoglobin and dissolved in plasma. More oxygen is transported by
hemoglobin, but oxygen is delivered to the tissues in dissolved form by the liquid portion of
blood. HBOT can increase in plasma oxygen to the tissues including the brain. A little change
in oxygen can make the better improvements in : cognitive ability, socialization, sleep,
calmness, decreased stimming and language. It can make increased in Glutathione (GSH), and
Glutathione (GSH) can decreased in oxidative stress with effected to remove metal compounds
(mercury) to improve the autism.

This clinical trial study divided into 3 group populations 1. general autism 2.
post-treatment chiropractic autism 3. medicated autism. This comparative study shows the
major clinical symptoms before and after the treatment with HBOT. This study results and
analysis are the most important for our further projects planning.

Hyperbaric oxygenation in fluid microembolism.

Because clinicians require objectively demonstrable neurological deficits to confirm a diagnosis, the recognition of embolic events in the nervous system is generally restricted to the effects of ischemic necrosis produced by arterial occlusion. However, magnetic resonance imaging (MRI) has shown that lesser degrees of damage associated with small emboli are common, especially in the mid brain, and are usually clinically silent. They are frequently associated with atheromatous embolism in the elderly, but microembolic debris, such as fat, is common in the systemic venous return of healthy people and generally trapped in the microcirculation of the lung being removed by phagocytosis. However, pulmonary filtration may fail and microemboli may also pass through an atrial septal defect in so-called ‘paradoxical’ embolism. Studies of bubbles formed on decompression in diving have demonstrated the importance of pulmonary filtration in the protection of the nervous system and that filtration is size dependant, as small bubbles may escape entrapment. Fluid and even small solid emboli, arresting in or passing through the cerebral circulation, do not cause infarction, but disturb the blood-brain barrier inducing what has been termed the ‘perivenous syndrome’.

Hyperbaric oxygen and cerebral physiology.

Abstract: Hyperbaric oxygen (HBO) therapy is defined by the Undersea and Hyperbaric Medical Society (UHMS) as a treatment in which a patient intermittingly breathes 100% oxygen under a pressure that is greater than the pressure at sea level [a pressure greater than 1...