Clinical Trial – Hyperbaric Oxygen Treatment Ameliorates Insulin Resistance

Obesity is an epidemic in Western society and is the biggest risk factor for insulin
resistance and type 2 diabetes. The investigators have preliminary evidence showing that
hyperbaric oxygen therapy rapidly increases insulin sensitivity in humans. This requires
confirmation in a larger population, and with this study the investigators will also test for
mechanisms how this occurs. The investigators suspect that modulation of hypoxia and stress
response proteins following changes in tissue oxygenation may contribute to these
improvements. This study has the potential to yield new and important insights into the
insulin resistance in obesity.