By doing this study, researchers hope to learn the following:
– If providing hyperbaric oxygen (HBO) therapy prior to an umbilical cord blood (UBC)
transplant will help to improve the homing process
– The safety of HBO administration in the setting of the UBC transplant
– The effects of HBO therapy on the engraftment process
A prospective, open labeled, randomized controlled clinical trial comparing the benefit of
both hyperbaric oxygen therapy and intrapancreatic stem cell infusion to standard medical
treatment alone for type 2 diabetes mellitus. Subjects will receive standard medical
treatment (SMT) with insulin and metformin for 4 months (evaluation phase). Then they will be
randomized into either the intervention group or the control group:
This is an observational research study whose purposes are to see the effects of repeated
hyperbaric oxygen therapy treatments on the levels of stem/progenitor cells in peripheral
circulating blood following five days of treatment, 90 minutes per day at 2.0 atmospheres
absolute in 100% USP Grade Oxygen. Hyperbaric oxygen has a greater oxygen concentration than
air at sea level. In this research, the concentration of oxygen will be twice the level of
oxygen at sea level.