by HBOT News | May 3, 2016 | Aging, Clinical Trials, HBOT Research
Recent studies show preliminary evidence of HBOT therapeutic effects on angiogenesis,
increased tissue blood flow and oxygenation correlated with tissue function.
Our primary hypothesis is that HBOT will have beneficial effects on the above mentioned
organs associated with aging-related malfunctions due to restored mitochondrial function,
mobilization of stem cells and induction of angiogenesis.
by HBOT News | Feb 9, 2016 | Bone Marrow Transplantation, Clinical Trials, HBOT Research
This is a pilot study to evaluate the efficacy of hyperbaric oxygen therapy (HBO2) for
mobilizing hematopoietic progenitor cells from bone marrow to blood. These cells are needed
for patients to undergo bone marrow transplantation and some patients fail to respond to
current best chemotherapy. HBO2 has been shown to trigger stem cell mobilization in other
patient populations and we plan to investigate whether this intervention can act in concert
with chemotherapeutic agents to allow poor mobilizer patients to achieve successful bone
marrow transplantation. Twenty patients will be identified by participating hematologists who
have failed to respond adequately to chemotherapy. When it is deemed appropriate to attempt
an additional stem cell mobilization protocol, these patients will be administered
chemotherapy as determined by their primary treating hematologist and additionally receive
daily HBO2 (2.5 atmospheres absolute [ATA] for 90 minutes) for 3-8 days. At intervals, blood
samples will be obtained as is the normal transplantation protocol practice to assess whether
adequate stem cells are present in blood for the patient to proceed with transplantation. The
project is anticipated to take one year to complete.
by HBOT News | May 9, 2006 | Autism, Clinical Trials, HBOT Research
Autism is a neurodevelopmental disorder that currently affects as many as 1 out of 166
children in the United States. Autism is considered by many to be a permanent condition with
little hope for improvement. Treatment for autism is centered on special schooling and
behavioral therapy; medical science currently has little to offer.
Recent research has discovered that some autistic individuals have decreased blood flow to
the brain, evidence of inflammation in the brain, and increased markers of oxidative stress.
Multiple independent single photon emission computed tomography (SPECT) and positron emission
tomography (PET) research studies have revealed hypoperfusion to several areas of the
autistic brain, most notably the temporal regions and areas specifically related to language
comprehension and auditory processing. Several studies show that diminished blood flow to
these areas correlates with many of the clinical features associated with autism including
repetitive, self-stimulatory and stereotypical behaviors, and impairments in communication,
sensory perception, and social interaction. Hyperbaric oxygen therapy (HBOT) has been used
with clinical success in several cerebral hypoperfusion syndromes including cerebral palsy,
fetal alcohol syndrome, closed head injury, and stroke. HBOT can compensate for decreased
blood flow by increasing the oxygen content of plasma and body tissues and can even normalize
oxygen levels in ischemic tissue. In addition, animal studies have shown that HBOT has potent
anti-inflammatory effects and reduces oxidative stress. Furthermore, recent evidence
demonstrates that HBOT mobilizes stem cells from human bone marrow which may aid recovery in
neurodegenerative diseases. Based upon these findings, it is hypothesized that HBOT will
improve symptoms in autistic individuals.
The purpose of this study is to determine if HBOT improves clinical outcomes in children with
autism. The study will also determine if HBOT changes markers of inflammation and oxidative
stress in autistic children.
by HBOT News | Nov 15, 2024 | Wound News
In a remarkable medical intervention, WWL-TV reports that Hyperbaric Oxygen Therapy (HBOT) was instrumental in saving a young girl’s nose following a severe dog bite. Five-year-old Lucy Nadler suffered a traumatic injury when a Labrador retriever bit off part of...
by HBOT News | May 7, 2024 | Amputation Stumps
The transformative benefits of Hyperbaric Oxygen Therapy (HBOT) continue to make waves in medical circles, as evidenced by the remarkable recovery story of patients undergoing treatment at Ingalls Family Care Center. HBOT is a medical treatment that enhances the...
