Abstract:
Osteoradionecrosis is one of the most serious and devastating complications of radiotherapy. The proper management of osteoradionecrosis is currently undetermined. The objective of this study is to evaluate the treatment results of a systematic approach to osteoradionecrosis. A prospective study of a systematic approach to osteoradionecrosis in the head and neck area was undertaken. From July 1993 to June 1998, 33 cases of osteoradionecrosis in the head and neck area were treated using a systematic approach that combined sequestrectomy and hyperbaric oxygen therapy. Seven (21%) had recurrent cancer. The control rate of the other 26 osteoradionecrosis cases was 77% (20/26).
Hao, Chen, Wei, Chen, Yeh, Su, , , (1999). Systematic management of osteoradionecrosis in the head and neck. The Laryngoscope, 1999 Aug;109(8):1324-7; discussion 1327-8. https://www.ncbi.nlm.nih.gov/pubmed/10443843