Feasibility and Efficacy of Enhanced Recovery After Surgery (ERAS) on Length of Stay Among Laparotomy Patients at Mbarara Regional Referral Hospital, Uganda

Description:

The efficacy of ERAS has been demonstrated in resource rich settings but limited evidence is
available from resource poor settings. The aim of this study was to determine the feasibility
and test efficacy of ERAS in reducing length of post-operative hospital stay and the
incidence of postoperative complications compared to the standard of care as the control
group.

33 participants above 18 years of age, undergoing laparotomy, were randomly assigned to an
intervention (ERAS) arm or to a control (standard surgical care) arm at Mbarara Regional
Referral Hospital in Uganda. The ERAS and the control arm had 16 and 17 patients
respectively, followed-up 14 days after surgery.

Patients in the ERAS arm had 2.4 days (SD 0.7) of post-operative hospital stay shorter than
those in the control arm, p=0.0025 (4.1±0.2 vs 6.5±0.6 respectively). 18.8% of patients in
the control arm developed post-operative complications compared to 5.9% in the ERAS arm
(Statistical insignificance, p=0.34). ERAS patients passed flatus eight hours earlier than
patients in the control arm, and mobilisation out of bed happened 12 hours earlier in the
ERAS group p value=0.4.

ERAS is feasible at Mbarara Regional Referral Hospital, and it leads to reduced hospital stay
duration but not post-operative complications in laparotomy cases.

Condition:

Laparotomy

Treatment:

Carbohydrate drink load

Start Date:

June 1, 2017

Sponsor:

Mbarara University of Science and Technology

For More Information:

https://clinicaltrials.gov/show/NCT03665376