Department of Anaesthesiology, Taipei Veterans General Hospita, Taipei, Taiwan
Description:
The activity of the autonomic nervous system is of fundamental importance in the regulation
of vital bodily functions. Unbalance of autonomic nerve system results in considerably
disordered vital function. Clinically, this is of great significance, because if an
anesthetic agent produces cause the sympathetic system to block, the effects can be serious
in individual cases, particularly on the cardiovascular system. If complications are to be
avoided, it is essential to assess the degree of block correctly. Clinical monitoring has a
variety of applications, a particularly useful one being measurement of the sympathetic
system during regional anesthesia, for which quantification of the blocking effect is a
clinical necessity and the degree of block needs to be ascertained without delay. The
autonomic nervous system (ANS) plays an important role in the regulation of hemodynamics
during anesthesia. Analysis of beat-to-beat fluctuations of heart rate and blood pressure is
a promising new approach to the clinical diagnosis and management of alterations in
cardiovascular regulation. Continuous Wavelet Transform (CWT), which could overcome the
limitation of the steady-state assumption in the classical spectral analysis, is believed as
a reliable and robust method to access cardiorespiratory dynamics of the ANS and the
investigators will applied during spinal anesthesia to evaluate the detail changes.
Condition:
Participants Scheduled for Surgery Under Spinal Anesthesia Without Impairment of Renal, Hepatic, Cardiac or Respiratory Function
Treatment:
observation study about the autonomic response after spinal anesthesia
Start Date:
March 1, 2019
Sponsor:
National Central University
For More Information:
https://clinicaltrials.gov/show/NCT04275375