Veterans Special Report
Acute Myeloid Leukemia

Clinical Trial – Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant

May 23, 2019 | , ,

Subjects with Acute Myeloblastic Leukemia (AML) and myelodysplastic syndrome (MDS) who are
considered eligible for allogeneic stem cell transplant by the transplant team at WCI (Wilmot
Cancer Institute)will be enrolled in the study. Patients will receive Melphalan on day -2 and
HBO (Hyperbaric Oxygen) therapy on day 0 of the transplant. After neutrophil recovery is
documented, the patients will be seen in clinic at least weekly through day +100.

Clinical Trial – Use of Hyperbaric Oxygen Therapy to Improve Umbilical Cord Blood Stem Cell Homing and Subsequent Engraftment

Mar 20, 2014 | , ,

By doing this study, researchers hope to learn the following:

– If providing hyperbaric oxygen (HBO) therapy prior to an umbilical cord blood (UBC)
transplant will help to improve the homing process

– The safety of HBO administration in the setting of the UBC transplant

– The effects of HBO therapy on the engraftment process

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