Chronic obliterative arteriopathy of the inferior limbs is a frequent condition observed in
diabetics. The later stages induce pain at rest and trophic disorders (ulcer, gangrene) that
lead to chronic limb ischemia. Without possible surgical revascularization ,pain management
and tissue healing are used to avoid amputation.

Prevalence of diabetes is twice higher in Reunion Island than in metropolitan France. As a
consequence, the rate co-morbobidities, such as chronic obliterative arteriopathy of the
inferior limbs, is also increases.

This study compares the efficiency of two analgesic treatments in diabetics with forefoot
injuries.