Abstract: Necrotizing fasciitis and myositis caused by group A streptococci (GAS) are among the most fulminating infections, with a mortality rate of 20% to 30%. Although numerous regimens have been utilized in attempts to control these devastating infections, such as...
Shivering is an unpleasant experience after spinal anesthesia. Shivering is defined as an
involuntary, repetitive activity of skeletal muscles. The mechanisms of shivering in patients
undergoing surgery are mainly intraoperative heat loss, increased sympathetic tone, pain, and
systemic release of pyrogens. Spinal anesthesia significantly impairs the thermoregulation
system by inhibiting tonic vasoconstriction, which plays a significant role in temperature
regulation. Spinal anesthesia also causes redistribution of core heat from the trunk (below
the block level) to the peripheral tissues. These two effects predispose patients to
hypothermia and shivering. The median incidence of shivering related to regional anesthesia
observed in a review of 21 studies is 55%. Shivering increases oxygen consumption, lactic
acidosis, carbon dioxide production, and metabolic rate by up to 400%. Therefore, shivering
may cause problems in patients with low cardiac and pulmonary reserves. The best way to avoid
these intraoperative and postoperative shivering-induced increases in hemodynamic and
metabolic demands is to prevent shivering in the first place. Although magnesium is among
several pharmacological agents used for the treatment of shivering, its effects on prevention
of shivering during central neuraxial blockade have not been evaluated to date. Henceforth,
the aim of this study was to evaluate the effect of magnesiume on shivering during spinal
anesthesia.
Aim:
to compare the efficacy of intravenous versus intrathecal magnesium sulphate for prevention
of post spinal shivering in adult patients undergoing elective lower limb orthopedic
surgeries.
İn this study; it was aimed to investigate the effects of equipotent doses of hyperbaric
bupivacaine and hyperbaric levobupivacaine in outpatient anorectal surgery under saddle
block. Sixty patients between the age of 18- 50 and in the risk group of ASA I-II included in
the study. 7,5 mg of 0,5% hyperbaric bupivacaine or 7,5 mg of 0,5% hyperbaric levobupivacaine
injected into the intrathecal space in sitting position through L4-L5 or L5-S1 intervertebral
space in 30 seconds. All patients kept in sitting position for 5 minutes with aid after
intrathecal injection and than layed in supine position, finally they positioned in prone
jack-knife. Hemodynamic parameters like NIBP, HR, SpO2, sensory and motor block
characteristics, duration of analgesia, time of first voiding, mobilization time, patient and
surgeon satisfaction, adverse effects and discharge time were recorded during and after
surgery.
Abstract: Hyperbaric oxygenation therapy is successfully implemented for the treatment of several disorders. Data on the effect of hyperbaric oxygenation on echocardiographic parameters in asymptomatic patients is limited. The current study sought to evaluate the...
The AC133 antigen is a novel antigen selectively expressed on a subset of CD34+ cells in human fetal liver, bone marrow, and blood as demonstrated by flow cytometric analyses. In this study, we have further assessed the expression of AC133 on CD34+ cells in hemopoietic samples and found that there was a highly significant difference between normal bone marrow and cord blood versus aphereses (p <0.0001) but not between bone marrow and cord blood. Most of the clonogenic cells (67%) were contained in the CD34+AC133+ fraction. Compared with cultures of the CD34+AC133- cells, generation of progenitor cells in long-term culture on bone marrow stroma was consistently 10- to 100-fold higher in cultures initiated with CD34+AC133+ cells and was maintained for the 8-10 weeks of culture.
This study evaluates the effect of subarachnoid hyperbaric bupivacaine on mean arterial blood
pressure (MAP) of pregnant patients with obesity undergoing cesarean section half of the
patients will receive subarachnoid hyperbaric bupivacaine at a dose of 5 mg while the other
half will receive a dose of 10 mg
Acute appendicitis which is the most common cause of acute abdominal pain, is an acute
inflammation of appendix vermiformis. Appendectomy operations can be performed as
laparoscopic and open surgery. Addition of opioids to intrathecal local anesthetics to
improve the quality of preoperative analgesia is an increasingly used method in recent years.
The aim of this study is to compare bupivacaine-fentanyl and bupivacaine-alfentanil which are
used intrathecally to create motor and sensory block. 50 volunteer patients who were
diagnosed as appendicitis by laboratory tests and clinical diagnostic methods in general
surgery clinic and classified as American Society of Anesthesiologists Classification I-II
(ASA Class I-II) aged between 20-60 years scheduled for laparoscopic appendectomy operation,
were included in this study. The patients were randomly assigned into two groups, Group I and
Group II. Patients received spinal anesthesia with either 10 mg heavy bupivacaine (2 cc)+25
mcg fentanyl (0.5 cc) intrathecally (Group I, n=25) or 10 mg heavy bupivacaine (2 cc)+250 mcg
alfentanil (0.5 cc) intrathecally (Group II, n=25).
Spinal anesthesia is the technique of choice in transurethral prostatectomy.However,one of
the common complications of spinal anesthesia is shivering which is even exaggerated in
patients undergoing transurethral prostatectomy.this high incidence is most probably caused
by sympathetic block and use of large amount of irrigation fluid during surgery.There are two
methods to reduce shivering.Previous studies showed that intrathecal fentanyl is an
appropriate method to reduce shivering.Intrathecal dexamethasone could reduce shivering by
regulating immune responses.
Audiological evaluation performed to patients on hyperbaric oxygen therapy to see its effects
on middle ear pressure
ABC13's Shelley Childers explains the treatment facility and the method used to help those like baby Dylan who nearly drowned. NEW ORLEANS, Louisiana (KTRK) -- Inside a small, indistinct building on the side of a busy street just south of New Orleans, small miracles...