Abstract During evolution, individuals whose brains and bodies functioned well in a fasted state were successful in acquiring food, enabling their survival and reproduction. With fasting and extended exercise, liver glycogen stores are depleted and ketones are...
Effects of hyperbaric oxygen treatment on implant osseointegration in experimental diabetes mellitus.
Abstract: To evaluate whether hyperbaric oxygen (HBO) treatment has a favorable effect on implant osseointegration in diabetic rabbits. An experimental diabetes model was induced in 32 New Zealand rabbits through IV injection of alloxan. After the state of diabetes...
Clinical Trial – Analgesic Efficacy of Two Adjuvants During Spinal Anaesthesia.
: Pain modulation is very important after operation, particularly for women who undergo
caesarean section. A pain-free postoperative period is essential following a caesarean
section so new mothers may care for and bond with their neonates. The consequences of the
improper pain management which raise the healthcare costs and prolong the recovery process.
Intrathecal adjuvants are often administered during this procedure to provide significant
analgesia, but they may also have bothersome side effects. Intrathecal midazolam and
magnesium sulfate produces effective postoperative analgesia with no significant side
effects.
Objectives: This prospective, randomized, double-blind study was designed to compare the
analgesic efficacy and safety of intrathecal midazolam vs. Magnesium sulfate vs plain
bupivacaine as an adjunct to bupivacaine in pregnancy patients scheduled for elective
caesarean section.
Beneficial Effect of β-Elemene Alone and in Combination with Hyperbaric Oxygen in Traumatic Brain Injury by Inflammatory Pathway.
Present study evaluates the neuroprotective effect of β-elemene alone and in combination with hyperbaric oxygen (HO) in traumatic brain injury (TBI). TBI was induced by dropping a weight from a specific height. All the animals were separated in to five groups (n=20) like control group; TBI group; β-elemene treated group which receives β-elemene (100 mg/kg, i.p.) half an hour after the injury; HO group which receives hyperbaric oxygen therapy and β-elemene + HO group which receives β-elemene (100 mg/kg, i.p.) half an hour after the injury and hyperbaric oxygen therapy. Neurological function was assessed to evaluate the effect of β-elemene in TBI rats. Thereafter level of inflammatory cytokines and expression of protein of inflammatory pathway was assessed in the brain tissues of TBI rats.
Iatrogenic cerebral gas embolism-A systematic review of case reports.
Abstract: Cerebral gas embolism is a complication of several medical procedures and occurs when gas enters the cerebral circulation. Knowledge about etiology and outcome in affected patients is limited, and prospective trials on management and treatment are hardly...
Clinical Trial – Continuous Spinal Anesthesia in Renal Transplantation
Renal transplantation is now recognized as a treatment of choice for patients with end-stage
renal disease. An adequate anesthetic technique should achieve hemodynamic stability and
enhance perfusion of the transplanted kidney. The aim of this study is to assess the use &
effects of continuous spinal anesthesia for kidney transplantation recipients, compared with
balanced general anesthesia.
Clinical Trial – Effect of Diabetes Mellitus on Spinal Block Criteria During Cesarean Section
The current study aimed at studying the effect of DM during pregnancy on the spinal block
criteria during C.S.
The primary end point of the trial is the incidence of complete failure of spinal block.
Secondary endpoint is to determine the effect of DM on the other spinal block criteria as
onset and duration of block, level of spinal block, rate of regression, hemodynamic changes,
doses of inotropes and incidence of complications
Methemoglobinemia treated with hyperbaric oxygen therapy: A case report.
Abstract: Methemoglobinemia is a rare but clinically important condition that should be considered among differential diagnosis' in cyanosis. The conventional treatments of methemoglobinemia are high flow oxygen and methylene blue therapies. We present a 52-year-old...
Carbon monoxide poisoning in a young, healthy patient: A case study of heart failure recovery after Hyperbaric Oxygenation Treatment.
Abstract: The effectiveness of hyperbaric oxygen treatment for acute cardiac diseases is unknown. Similarly, the effectiveness of hyperbaric oxygen treatment for carbon monoxide intoxication is also unknown, particularly for cases in which carboxyhemoglobin (COHb)...
Clinical Trial – Incidence of Postoperative Delirium in Cancer Patients After Laparoscopic Surgery in Trendelenburg Position
Postoperative delirium is an acute mental syndrome that is caused by diffuse cerebral
dysfunction resulting from the action of predisposing and precipitating factors acting
together. It is associated with an increase in mortality and postoperative morbidity and
prolongs the period of hospitalization of the patient Videolaparoscopic surgery has been
increasingly used as a therapeutic and diagnostic method. In order to have a good
visualization of the anatomical structures on which it will act, it is necessary to introduce
gas into the cavity, a mandatory component known as pneumoperitoneum. This technique gives
special characteristics for the conduction of anesthesia, since the positive intra-abdominal
pressure results in changes in the patient’s physiology. Some types of laparoscopic surgery
require the position of Trendelenburg for better visualization of the operative field. Among
the changes related to this position are the increase in cardiac output and intracranial
pressure.
In order to optimize the anesthetic procedure, anesthetic blocks have been increasingly used,
especially the spinal. The association of general anesthesia with spinal anesthesia, followed
by its contraindications is advantageous, because lower doses of anesthetic agents are
necessary for the maintenance of general anesthesia. This association results in an earlier
awakening, a reduction of nausea / vomiting, postoperative pain, length of hospital stay,
cost effectiveness and greater patient satisfaction. As a disadvantage, by associating
general anesthesia with spinal anesthesia, patients become susceptible to the adverse events
of spinal anesthesia. Among these, the most common are headache, hypotension, nausea and
vomiting, pruritus, urinary retention and tremor. Performing spinal anesthesia with opioids
alone, without the use of local anesthetic is also possible, with morphine being the most
used. The benefit of this variation of technique is analgesia for a period of 12 to 24 hours,
without the cardiovascular consequences resulting from the action of the local anesthetic.
JUSTIFICATION: There are no studies in the literature evaluating The objective of this study
is to analyze if the anesthetic techniques employed, general anesthesia or general anesthesia
associated with subarachnoid block, for videolaparoscopic oncologic surgeries, in
Trendelenburg position, differ in relation to the incidence of delirium in the postoperative
period.

