Abstract: The glans penis may show a deep groove (surgically favorable), or may appear flat with an absent sulcus (unfavorable). Glans dehiscence following hypospadias repair, especially after multiple surgeries, frequently results in a scarred, obliterated, or absent...
HBOT Research
Clinical Trial – Dosage of Intrathecal Hyperbaric Bupivacaine and the Incidence of Post Spinal Shivering.
Shivering is very common after spinal anaesthesia. Many studies have investigated the role of
adding adjuvants to the local anaesthetics to decrease the incidence of post-spinal
shivering. Non of the studies n the literature review have investigated the role of different
dose of local anaesthetic alone in reducing the incidence of post-spinal shivering. In the
present study the investigators aimed to compare the effect of different local anaesthetic
dose in reducing post-spinal shivering.
Clinical Trial – Peripheral Analgesia in Painful Diabetic Neuropathy
Chronic obliterative arteriopathy of the inferior limbs is a frequent condition observed in
diabetics. The later stages induce pain at rest and trophic disorders (ulcer, gangrene) that
lead to chronic limb ischemia. Without possible surgical revascularization ,pain management
and tissue healing are used to avoid amputation.
Prevalence of diabetes is twice higher in Reunion Island than in metropolitan France. As a
consequence, the rate co-morbobidities, such as chronic obliterative arteriopathy of the
inferior limbs, is also increases.
This study compares the efficiency of two analgesic treatments in diabetics with forefoot
injuries.
Case control study: hyperbaric oxygen treatment of mild traumatic brain injury persistent post-concussion syndrome and post-traumatic stress disorder.
Mild traumatic brain injury (TBI) persistent post-concussion syndrome (PPCS) and post-traumatic stress disorder (PTSD) are epidemic in United States Iraq and Afghanistan War veterans. Treatment of the combined diagnoses is limited. The aim of this study is to assess safety, feasibility, and effectiveness of hyperbaric oxygen treatments (HBOT) for mild TBI PPCS and PTSD. Thirty military subjects aged 18-65 with PPCS with or without PTSD and from one or more blast-induced mild-moderate traumatic brain injuries that were a minimum of 1 year old and occurred after 9/11/2001 were studied. The measures included symptom lists, physical exam, neuropsychological and psychological testing on 29 subjects (1 dropout) and SPECT brain imaging pre and post HBOT.
Intralesional epidermal growth factor therapy fordiabetic foot ulcers: an evaluation of 15 cases
Abstract: Background/aim: Intralesional recombinant epidermal growth factor (EGF) is a new treatment approach for diabetic foot ulcer, approved in 2006. EGF therapy is given as an adjunct to the standard treatment regimen of antibiotics, surgery, and hyperbaric...
Clinical Trial – Effects of Analgesics in Cesarean Section Elective
Two approved treatments for spinal anesthesia will be compared in women undergoing cesarean
section.
It is usual to perform cesarean sections using spinal anesthesia with a local anesthetic
(bupivacaine) plus some opioid, such as sufentanil or morphine. Both have been shown to
decrease postoperative pain, but we try to check if one brings more benefit than the other.
Hyperbaric Oxygen Therapy in the Treatment of Acute Severe Traumatic Brain Injury: a Systematic Review.
There has been no major advancement in a quarter of a century for the treatment of acute severe traumatic brain injury (TBI). This review summarizes 40 years of clinical and pre-clinical research on the treatment of acute TBI with hyperbaric oxygen therapy (HBO2) in the context of an impending National Institute of Neurologic Disorders and Stroke (NINDS)-funded, multicenter, randomized, adaptive Phase II clinical trial – the Hyperbaric Oxygen Brain Injury Treatment (HOBIT) trial. Thirty studies (8 clinical and 22 pre-clinical) that administered HBO2 within 30 days of a TBI were identified from PubMed searches. The pre-clinical studies consistently reported positive treatment effects across a variety of outcome measures with almost no safety concerns, thus providing strong proof-of-concept evidence for treating severe TBI in the acute setting.
Clinical Trial – Hyperbaric Oxygen and Manipulative Therapies to Regain Function Post Stroke
To study safety, feasibility and outcomes of combining osteopathic manipulative therapies
with hyperbaric oxygen therapy in reducing the functional deficits in stroke survivors in
subacute and chronic phases post ischemic stroke. To document the same as part of a pilot
project in anticipation of further investigational studies.
A diabetic foot ulcer treated with hydrogel and hyperbaric oxygen therapy: a case study.
Abstract: This study reports on the case of an elderly patient, with diabetes, and a bullous wound on the left big toe that led to an amputation of the first and second left toes. The amputation was because of deep injury as it was not able to heal with a conventional...
The sausage toe as a sign of diabetic foot osteomyelitis.
Abstract: Mutluoglu, Ercengiz, Yazici Mutlu, Memis (2017). The sausage toe as a sign of diabetic foot osteomyelitis. International wound journal, 2017 Dec;():. https://www.ncbi.nlm.nih.gov/pubmed/29266830