Abstract: We present a case report on the successful healing of a Pseudomonas infection wound in a 52-year-old female with morbid obesity, noninsulin dependent diabetes mellitus and a history of tobacco use, who presented with Stage IIIA (T3, N2, Mo) infiltrating...
HBOT Research
Efficacy of Metabolically Supported Chemotherapy Combined with Ketogenic Diet, Hyperthermia, and Hyperbaric Oxygen Therapy for Stage IV Triple-Negative Breast Cancer.
Abstract: Triple-negative breast cancer (TNBC) is more aggressive and metastatic than other breast cancer types. Cytotoxic chemotherapy is presently the predominant systemic therapy for TNBC patients. This case report highlights the influence of metabolically...
Do Allogeneic Blood Transfusions Cause Infection?
Abstract: Shander, Ozawa, Brower, , , , , , (2017). Do Allogeneic Blood Transfusions Cause Infection? Anesthesia and analgesia, 2017 10;125(4):1092-1094. https://www.ncbi.nlm.nih.gov/pubmed/28922217
Refractory Ulcerated Necrobiosis Lipoidica: Closure of a Difficult Wound with Topical Tacrolimus.
Abstract: To report a case of refractory ulcerated necrobiosis lipoidica (NL) with significant response to treatment with topical tacrolimus. A 55-year-old woman without diabetes and with a previous history of NL presented to the Helen L. and Martin S. Kimmel...
Hyperbaric oxygen therapy: An alternative treatment for radiation-induced cutaneous ulcers.
Abstract: Radiotherapy is a widely recognised treatment for non-melanoma skin cancer. We report three cases of radiation-induced skin ulcers in which hyperbaric oxygen therapy was administered in 90-min sessions, 5 days a week at 2.4 absolute atmospheres in a...
miR-491-5p inhibits osteosarcoma cell proliferation by targeting PKM2.
Abstract: Increasing evidence has indicated that microRNAs (miRNAs/miRs) are associated with tumorigenesis and the development of numerous cancer types. Previous studies have suggested miRNA-491-5p is downregulated in osteosarcoma (OS) and functions as a tumor...
Clinical Trial – Acute Postthoracotomy Pain – Impact of Gender
Adequate analgesia in thoracic surgery is essential to prevent severe postoperative
complications, especially respiratory problems. Current knowledge about gender-related
differences in pain states generally more frequent and intense pain and more demand for
analgesics in women. Results about postsurgical pain in particular are very inconclusive.
The investigators tried to find out if gender has an influence on postthoracotomy pain and
analgesics requirement.
Successful treatment of central retinal artery occlusion using hyperbaric oxygen therapy.
Abstract: Central retinal artery occlusion (CRAO) is considered an ophthalmologic emergency. The prognosis of this disease is very poor. Currently, there is no generally effective therapy available to treat CRAO. Hyperbaric oxygen therapy (HBOT) can increase the...
Hyperbaric oxygen-associated seizure leading to stroke.
Oxygen toxicity seizures are a well-known complication of hyperbaric oxygen treatment (HBOT). Until now, there have not been any reported cases of an acute ischaemic event (stroke) as the result of a HBOT-associated oxygen toxicity seizure. We report an event in which a seizure and stroke occurred together and consider that the stroke may have been caused by seizure-induced demand ischaemia. This challenges the generally held view that oxygen toxicity seizures in the clinical hyperbaric setting are benign. A discussion of the literature on the subject of seizure-induced brain injury is included. Risk factors for cerebrovascular disease should be taken into consideration in determining treatment pressures for HBOT, as reducing pressure reduces seizure risk.
Functional Medicine Approach to Traumatic Brain Injury.
Background: The U.S. military has seen dramatic increases in traumatic brain injuries (TBIs) among military personnel due to the nature of modern-day conflicts. Conventional TBI treatment for secondary brain injuries has suboptimal success rates, and patients, families, and healthcare professionals are increasingly turning to alternative medicine treatments. Objective: Effective treatments for the secondary injury cascades that occur after an initial brain trauma are unclear at this time. The goal of successful treatment options for secondary TBI injuries is to reduce oxidative stress, excitotoxicity, and inflammation while supporting mitochondrial functions and repair of membranes, synapses, and axons.