Intraoperative pain, nausea, vomiting, hypotension, bradycardia are known side effects during
lower abdominal surgery under spinal anesthesia, Time to 2 segment regression of sensory
block and duration of effective analgesia prolonged with intrathecal (IT) 0.4 mg nalbuphine &
IT 0.8 mg nalbuphine, but the incidence of side-effects was significantly higher with IT 0.8
mg nalbuphine compared with (IT) 0.4 mg nalbuphine.
HBOT Research
Proliferative retinopathy during hyperbaric oxygen treatment.
Abstract: A 43-year-old male with type 2 diabetes mellitus, treated with insulin for 28 years and with an HbA1c of 7.9% six months prior, suffered from bilateral plantar ulcers refractory to specialised wound care. He underwent a planned 40 sessions of hyperbaric...
Hyperbaric oxygen in the treatment of acute retinal artery occlusion.
Abstract: Acute retinal artery occlusion (ARAO) is a major cause of sudden, painless visual loss, often leaving no useful vision in the affected eye. Its incidence is cited at 0.85 per 100,000 persons per year but may be higher because of under-reporting. The natural...
Associations of Plasma Nitrite, L-Arginine and Asymmetric Dimethylarginine with Morbidity and Mortality in Patients with Necrotizing Soft Tissue Infections.
Abstract: The nitric oxide system could play an important role in the pathophysiology related to necrotizing soft tissue infection (NSTI). Accordingly, we investigated the association between plasma nitrite level at admission and the presence of septic shock in...
Cervical Necrotizing Fasciitis of Odontogenic Origin and Hyperbaric Oxygen Therapy.
Abstract: Necrotizing fasciitis (NF) is an infection of the soft tissues pathology with high mortality that spreads through the fascial planes and rarely seen in head and neck region. The cause of infection is often odontogenic problems. Broad-spectrum antibiotics,...
Is There a Place for Ozone Therapy in Patients with Heart Failure?
Abstract: Clavo, Eltobgy, Caballero, Abad, Rodríguez-Esparragón, Santana-Rodríguez, , , (2017). Is There a Place for Ozone Therapy in Patients with Heart Failure? Cardiovascular toxicology, 2017...
Clinical Trial – The RESPOND Registry
The RESPOND Registry is an observational study to assess the impact of PuraPly™ AM on the
management of wounds in real world clinical settings; no experimental intervention is
involved.
Hyperbaric Oxygen Therapy after Acute Thoracic Spinal Cord Injury: Improvement of Locomotor Recovery in Rats.
The aim of this study was to analyze the effectiveness of hyperbaric therapy (HT) using mild and moderate models of spinal cord injury (SCI). SCI can cause permanent impairment with socioeconomic consequences. The motor deficit occurs by two mechanisms: destruction of neuronal cells and local inflammatory response, resulting in hypoxia. HT acts by increasing oxygen in the injured area. Thoracic laminectomy was performed in 72 female Wistar rats. The MASCIS impactor was used at 12.5 mm (n = 35) and 25 mm (n = 35) of height to perform, respectively, mild and moderate SCI. Muscle strength was assessed through the Basso, Beattie, and Bresnahan scale (BBB) on days 1, 7, 14, 21, and 28 after SCI. The animals were randomized into five subgroups with seven animals each: (1) control group had SCI without HT; (2) HT 30 minutes after SCI; (3) HT 30 minutes after SCI and daily for 7 days; (4) HT 12 hours after SCI; and (5) HT 12 hours after SCI and daily for 7 days. HT was performed at 2.5 atm for 1 hour.
Clinical Trial – Transversus Abdominis Plane Block Versus Spinal Morphine After Caesarean Section : A Comparison Study
Many counties in sub-Saharan Africa have very limited post-operative nursing capacity, and
relatively little data have been published about post-operative maternal pain control in
these settings. Cesarean section is the most common type of major operation at our
institution, Mbarara Regional Referral Hospital (MRRH), in south-western Uganda.Nursing ward
staffing capacity is low, with much basic nursing care provided by families and friends of
patients. The investigators conducted a study to examine the impact of ITM versus TAP block
in a setting of limited formal nursing oversight.
Author response: Hyperbaric oxygen: B-Level evidence in mild traumatic brain injury clinical trials.
Abstract: Figueroa, Wright, (2017). Author response: Hyperbaric oxygen: B-Level evidence in mild traumatic brain injury clinical trials. Neurology, 2017 Aug;89(7):750-751. https://www.ncbi.nlm.nih.gov/pubmed/28808167