Abstract: As a hallmark of platelet activation, mean platelet volume (MPV) has been identified to be associated with various malignancies. However, the correlation between MPV, mean platelet volume/platelet count ratio (MPR), and esophageal squamous cell carcinoma...
HBOT Research
Therapeutic use of hyperbaric oxygen therapy for children with autism spectrum disorder
Autism spectrum disorder (ASD) is neurodevelopment disorder, characterized by impairment in social interaction, verbal and non-verbal communication and the presence of restricted and repetitive stereotyped behaviors. The condition manifests within the first 3 years of life and persists till adulthood. At present, the etiology of ASD is largely unknown, but genetic, environmental, immunological, and neurological factors are thought to play a role in the development of ASD. The prevalence of ASD has increased dramatically in the past few decades. According to current estimates from the United States Centers for Disease Control and Prevention (CDC) as many as 1 in 91 children have ASD in USA.
Amputation predictors in diabetic foot ulcers treated with hyperbaric oxygen.
Abstract: Although hyperbaric oxygen therapy (HBOT) has long been used for diabetic foot ulcers (DFUs), its effectiveness is still controversial. The aim of this study was to investigate the efficacy of HBOT in the management of DFUs and identify amputation...
Clinical Trial – Spinal Prilocaine for Caesarian Sections
Prilocaine theoretically could provide faster onset because of its lower pKa (7,7) compared
to bupivacaine (8,1). The primary objective of this prospective double blind randomized trial
is to determine block onset of spinal hyperbaric prilocaine compared to bupivacaine, both
with a small dose of sufentanyl as an additive.The primary hypothesis is that a significant
larger amount of patients will gain surgical readiness within 8 minutes after spinal
injection of prilocaine with sufentanyl compared to bupivacaine with sufentanyl. Surgical
readiness is defined as a sensory block level of T5 tested by loss of cold sensation.
The Role of Hyperbaric Oxygen Therapy in Orthopedics and Rheumatological Diseases.
Abstract: Hyperbaric oxygen therapy (HBOT) has been investigated as a primary/adjunctive treatment for a number of injuries and medical conditions including traumatic ischemia, necrotizing soft tissue injuries, non-healing ulcers and osteoradionecrosis, but the...
Chronic Diseases as Barriers to Oxygen Delivery: A Unifying Hypothesis of Tissue Reoxygenation Therapy.
Abstract: Modern medical practice has resulted in the accumulation of a growing number of incurable chronic diseases, many of which are inflammatory in nature. Inflammation establishes a hypoxic microenvironment within tissues, a condition of inflammatory hypoxia...
Chronic Diseases as Barriers to Oxygen Delivery: A Unifying Hypothesis of Tissue Reoxygenation Therapy.
Abstract: Modern medical practice has resulted in the accumulation of a growing number of incurable chronic diseases, many of which are inflammatory in nature. Inflammation establishes a hypoxic microenvironment within tissues, a condition of inflammatory hypoxia...
Hyperbaric Oxygen Therapy as Adjuvant Treatment for Hardware-Related Infections in Neuromodulation.
Abstract: In neuromodulation therapies, hardware-related infections are a major challenge often leading to hardware removal. To investigate the role of adjuvant hyperbaric oxygen therapy (HBOT) in hardware-related infections. Fourteen hardware-related infection events...
A Systematic Review of the Causes and Management of Ischaemic Stroke Caused by Nontissue Emboli.
Abstract: The inadvertent or purposeful introduction of foreign bodies or substances can lead to cerebral infarction if they embolize to the brain. Individual reports of these events are uncommon but may increase with the increased occurrences of their risk factors,...
Calcitriol promotes proangiogenic molecules in keratinocytes in a diabetic foot ulcer model.
Abstract: Foot ulceration is one of the most common and complex sequelae of diabetes mellitus, generally posing a therapeutic challenge due to poor healing responses and high rates of complications, including peripheral vascular disease, ischemia and infections....