Addition of Lidocaine to Levobupivacaine Reduces Intrathecal Block Duration: Randomized Controlled Trial
Description:
A satisfactory spinal anaesthesia requires both a fast onset and proper duration at the same
time. Transurethral resection of the prostate (TUR-P) is a surgery of medium duration. The
addition of lidocaine to hyperbaric bupivacaine shortens the duration of bupivacaine spinal
block and therefore provides more rapid recovery. This property of lidocaine is not verified
with other local anesthetics. Levobupivacaine is a S-enantiomer of racemic bupivacaine and is
a long acting local anesthetic.The aim of this prospective randomized controlled study was to
investigate this effect of lidocaine, with a local anesthetic other than bupivacaine. It was
hypothesized that the duration of the intrathecal block could change when performed with
hyperbaric levobupivacaine mixed with low dose lidocaine and this technique could be
consistent for the duration of TUR-P surgery. Participants will be followed on the day of
surgery for primary and secondary outcome measures and 3 days postoperatively for
complications (TNS).
Condition:
Benign Prostate Hyperplasia
Treatment:
Levobupivacaine lidocaine spinal anesthesia
Start Date:
July 2009
Sponsor:
Diskapi Teaching and Research Hospital
For More Information:
https://clinicaltrials.gov/show/NCT01675895