A Prospective Study on Efficacy of Hyperbaric Oxygenation Treatment for Patients With Trigeminal Neuralgia: a Randomized, Double-Blind, Mock Hyperbaric Chamber -Controlled, Parallel-Group Trial
Description:
Trigeminal neuralgia(TN) is a recurrent severe shooting neuropathic pain. Treatment of this
pain continues to be a challenge in clinical pain management. Hyperbaric oxygen (HBO) has
been used of neuropathic diseases, which can improve blood partial pressure of oxygen, reduce
edema, relieve neural oppression and attenuate inflammatory response. The hypothesis of this
protocol is that hyperbaric oxygen treatment could relieve neuropathic pain and improve the
quality of life in TN patients. Visual analogue scale (VAS) and the mcgill pain questionnaire
(MGPQ) will be assessed before the initiation of the study, after hyperbaric oxygen (HBO)
treatment and at monthly intervals for the subsequent 3 months. Titration of dosage and pain
frequency will be recorded throughout the study. Clinical global impression (CGI) by the
individual patient will be evaluated at monthly intervals after HBO treatment.
Condition:
Trigeminal Neuralgia
Treatment:
Hyperbaric oxygen, Mock hyperbaric chamber
Start Date:
April 2008
Sponsor:
Xijing Hospital
For More Information:
https://clinicaltrials.gov/show/NCT00866424