The Analgesic Effects of Intrathecal Morphine in Comparison to Ultrasound-guided Transversus Abdominis Plane Block After Cesarean Section: a Randomized Controlled Trial at a Ugandan Regional Referral Hospital

Description:

Intrathecal morphine (ITM), administered as a part of spinal anesthesia for caesarian
section, can produce significant post-operative analgesia for several hours. The Tranversus
Abdominis Plane (TAP) Block can also provide prolonged post-operative pain control. A small
number of published studies comparing analgesic outcomes after cesarian section with ITM or
TAP block have reported variable results.Moreover, these studies have been conducted in
countries with extensive post-operative nursing care.

Many counties in sub-Saharan Africa have very limited post-operative nursing capacity, and
relatively little data have been published about post-operative maternal pain control in
these settings. Cesarean section is the most common type of major operation at our
institution, Mbarara Regional Referral Hospital (MRRH), in south-western Uganda.Nursing ward
staffing capacity is low, with much basic nursing care provided by families and friends of
patients. The investigators conducted a study to examine the impact of ITM versus TAP block
in a setting of limited formal nursing oversight.

Condition:

Pregnancy, Ceasarian Section, Anaesthesia

Treatment:

Intrathecal morphine

Start Date:

March 15, 2014

Sponsor:

Mbarara University of Science and Technology

For More Information:

https://clinicaltrials.gov/show/NCT03263689