Hyperbaric treatment for children with autism: a multicenter, randomized, double-blind, controlled trial.
Several uncontrolled studies of hyperbaric treatment in children with autism have reported clinical improvements; however, this treatment has not been evaluated to date with a controlled study. We performed a multicenter, randomized, double-blind, controlled trial to assess the efficacy of hyperbaric treatment in children with autism. 62 children with autism recruited from 6 centers, ages 2-7 years (mean 4.92 +/- 1.21), were randomly assigned to 40 hourly treatments of either hyperbaric treatment at 1.3 atmosphere (atm) and 24% oxygen (“treatment group”, n = 33) or slightly pressurized room air at 1.03 atm and 21% oxygen (“control group”, n = 29). Outcome measures included Clinical Global Impression (CGI) scale, Aberrant Behavior Checklist (ABC), and Autism Treatment Evaluation Checklist (ATEC).
A review of recent reports on autism: 1000 studies published in 2007.
Abstract: From 1000 studies published in 2007 on all aspects of autism, those that reached clear conclusions or included quantitative data were selected for this review. Possible etiologies include elemental metals, especially the inconsistent evidence regarding...Clinical Trial – Pilot Study of the Effect of Hyperbaric Oxygen Treatment on Behavioral and Biomarker Measures in Children With Autism
The purpose of this study is to increase the understanding of the effect of Hyperbaric Oxygen
Treatment (HBOT) on the behavior and functioning of children with autism. The main goal of
this study is to demonstrate that HBOT is safe and tolerable in autistic children, and to
measure the effect of HBOT on specific chemicals in their blood that may play a role in the
child’s behavior.