Osteonecrosis of the jaw after a single bisphosphonate infusion in a patient with metastatic renal cancer treated with sunitinib.
Abstract: Osteonecrosis of the jaw (ONJ) is recognised as an important adverse effect of intravenous bisphosphonates. Recent reports have suggested that antiangiogenic agents may promote the development of this condition. We report a case of ONJ occurring within days...Clinical Trial – Hyperbaric Oxygen Therapy in Treating Long-Term Gastrointestinal Adverse Effects Caused by Radiation Therapy in Patients With Pelvic Cancer
RATIONALE: Radiation therapy can cause long-term adverse effects. Hyperbaric oxygen therapy
may be effective in lessening gastrointestinal symptoms caused by radiation therapy given for
pelvic cancer. It is not yet known whether high-pressure oxygen is effective in treating
adverse effects caused by radiation therapy.
PURPOSE: This randomized phase III trial is studying hyperbaric oxygen therapy to see how
well it works in treating long-term gastrointestinal adverse effects caused by radiation
therapy in patients with pelvic cancer.