Clinical Trial – The Effect of Hyperbaric OxygeN Therapy on brEast Cancer Patients With Late Radiation toxicitY – UMBRELLA HONEY Trial
The "Hyperbaric OxygeN therapy on brEast cancer patients with late radiation toxicity"
(HONEY) trial aims to evaluate the effectiveness of HBOT on late radiation toxicity in breast
cancer patients using the trial within cohorts (TwiCs) design.
Clinical Trial – Acute Post-Radiation Hyperbaric Oxygen (HBO2) for Breast Cancer Patients Who Have Recently Completed Radiation Therapy
This study aims to compare patients that receive hyperbaric oxygen or Trental and Vitamin E
immediately after completion of radiation therapy to evaluate which treatment best reduces
radiation fibrosis.
Clinical Trial – Hyperbaric Radiation Sensitization of Head and Neck Cancers
There is reason to believe that hyperbaric oxygen administered immediately prior to
radiotherapy will prove beneficial for this cancer type and stage. The basis for this
hypothesis is a review of several decades of published work, the conclusion of a recent
(2018) Cochrane Review, and results of a Phase I trial.
Hyperbaric oxygen therapy for postoperative ischemic bronchitis after resection of lung cancer.
Hyperbaric oxygen therapy (HBOT) has been used successfully in the treatment of specific ischemic injuries, but has been a little evaluated specifically in postoperative ischemic bronchitis (POIB). The purpose of this study was to evaluate the effect of HBOT when used for POIB after resection of lung cancer. From January 1999 to December 2016, 1,100 patients underwent lymph node dissection (LND) and either anatomic pulmonary resection or lung resection with bronchoplasty for lung cancer. POIB was diagnosed by bronchoscopy. HBOT was administered after POIB was diagnosed. HBOT comprised one 60-minute session daily in the hyperbaric chamber at 2.0 absolute atmospheres with 100% oxygen.