Hyperbaric oxygen for patients with chronic bowel dysfunction after pelvic radiotherapy (HOT2): a randomised, double-blind, sham-controlled phase 3 trial.
Abstract: Hyperbaric oxygen has been used as a therapy for patients experiencing chronic intestinal syndromes after pelvic radiotherapy for decades, yet the evidence to support the use of this therapy is based almost exclusively on non-randomised studies. We aimed to...Pelvic radiation disease: Updates on treatment options.
Abstract: Pelvic cancers are among the most frequently diagnosed neoplasms and radiotherapy represents one of the main treatment options. The irradiation field usually encompasses healthy intestinal tissue, especially of distal large bowel, thus inducing...The efficacy of pentoxifylline/tocopherol combination in the treatment of osteoradionecrosis.
Abstract: Osteoradionecrosis (ORN) is an unfortunate complication of radiation therapy to the head and neck. Treatment has historically centered around hyperbaric oxygen therapy and surgical removal of necrotic bone. Recently, a new theory on the pathogenesis of ORN...Clinical Trial – Hyperbaric Oxygen and Its Effect on Radiation Induced Long Term Side Effects
The investigators intend to determine if patients that are already undergoing Hyperbaric
Oxygen (HBO) therapy one year post treatment with radiation therapy for head and neck cancer,
experience improvement in xerostomia and/or taste alteration. The investigators will enroll a
similar demographic one year post treatment with radiation therapy that does not receive HBO
therapy. This is a quality of life study.